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Catalog Number:
04113
CAS Number:
146727-62-0
Boc-4-cyano-D-phenylalanine
Purity:
≥ 100% (HPLC)
Synonym(s):
Boc-D-Phe(4-CN)-OH, Boc-p-cyano-D-Phe-OH
Documents
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Product Information

Boc-4-cyano-D-phenylalanine is a versatile amino acid derivative that plays a significant role in peptide synthesis and drug development. This compound is particularly valued for its ability to introduce a cyano group, which can enhance the biological activity of peptides. Its unique structure allows for the incorporation of the Boc (tert-butyloxycarbonyl) protecting group, making it an ideal choice for researchers looking to create stable and functional peptides. The compound's properties facilitate its use in various applications, including the design of novel therapeutics and the study of protein interactions.

In the pharmaceutical industry, Boc-4-cyano-D-phenylalanine is utilized in the development of peptide-based drugs, where its ability to modify peptide properties can lead to improved efficacy and selectivity. Additionally, it serves as a valuable building block in the synthesis of complex molecules, enabling researchers to explore new avenues in medicinal chemistry. Its compatibility with standard coupling reagents and methods further enhances its appeal, making it a preferred choice for professionals engaged in peptide research and development.

Synonyms
Boc-D-Phe(4-CN)-OH, Boc-p-cyano-D-Phe-OH
CAS Number
146727-62-0
Purity
≥ 100% (HPLC)
Molecular Formula
C15H18N2O4
Molecular Weight
290.3
MDL Number
MFCD00672527
PubChem ID
4393346
Melting Point
154 - 157 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -8 ± 1° (C=1.034% in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Phe(4-CN)-OH, Boc-p-cyano-D-Phe-OH
CAS Number
146727-62-0
Purity
≥ 100% (HPLC)
Molecular Formula
C15H18N2O4
Molecular Weight
290.3
MDL Number
MFCD00672527
PubChem ID
4393346
Melting Point
154 - 157 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -8 ± 1° (C=1.034% in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-cyano-D-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceutical agents. Its protective Boc group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: Researchers leverage its unique properties to design and optimize drug candidates, especially in the field of cancer therapy, where it can be incorporated into compounds targeting specific pathways.
  • Bioconjugation: The presence of the cyano group enables bioconjugation techniques, allowing for the attachment of biomolecules to therapeutic agents, which is crucial in creating targeted drug delivery systems.
  • Analytical Chemistry: It is used as a standard in analytical methods, aiding in the quantification of similar compounds in complex mixtures, which is essential for quality control in pharmaceutical manufacturing.
  • Research in Neuroscience: This compound is explored in studies related to neurotransmitter systems, providing insights into the mechanisms of action for various neuroactive substances, thus contributing to advancements in neuropharmacology.

Citations