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Catalog Number:
04103
CAS Number:
205526-23-4
Fmoc-3-chloro-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Phe(3-Cl)-OH, Fmoc-m-chloro-D-Phe-OH
Documents
$22.03 /1G
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Product Information

Fmoc-3-chloro-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective protection of the amino group during the synthesis of peptides. Its chlorinated phenyl side chain enhances the compound's reactivity and provides valuable insights into structure-activity relationships, making it an essential tool for researchers in medicinal chemistry and biochemistry.

In practical applications, Fmoc-3-chloro-D-phenylalanine is particularly beneficial in the development of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its ability to introduce specific functional groups allows for the modification of peptide properties, enhancing their efficacy and stability. Researchers can leverage this compound to explore novel peptide designs, potentially leading to breakthroughs in drug discovery and development. With its unique properties and applications, Fmoc-3-chloro-D-phenylalanine stands out as a valuable asset for professionals in the pharmaceutical and biotechnology industries.

Synonyms
Fmoc-D-Phe(3-Cl)-OH, Fmoc-m-chloro-D-Phe-OH
CAS Number
205526-23-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20ClNO4
Molecular Weight
421.9
MDL Number
MFCD00672549
PubChem ID
6915685
Melting Point
121 - 126 ?C
Appearance
White powder
Optical Rotation
[a]20D = 34 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(3-Cl)-OH, Fmoc-m-chloro-D-Phe-OH
CAS Number
205526-23-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H20ClNO4
Molecular Weight
421.9
MDL Number
MFCD00672549
PubChem ID
6915685
Melting Point
121 - 126 ?C
Appearance
White powder
Optical Rotation
[a]20D = 34 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-chloro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the design of novel therapeutic peptides, particularly in the development of targeted drug delivery systems that can improve efficacy and reduce side effects.
  • Bioconjugation: Researchers use it to create bioconjugates, linking peptides to various biomolecules for applications in diagnostics and therapeutics, enhancing specificity in targeting.
  • Research in Neuroscience: The compound is valuable in studying neuropeptides, which are critical for understanding neurological functions and developing treatments for neurodegenerative diseases.
  • Protein Engineering: It aids in the modification of proteins to study structure-function relationships, providing insights that can lead to advancements in biotechnology and pharmaceuticals.

Citations