Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
04102
CAS Number:
198560-44-0
Fmoc-3-chloro-L-phenylalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-L-Phe(3-Cl)-OH, Fmoc-m-chloro-L-Phe-OH, (S-Fmoc-2-amino-3-(3-chlorophenyl)propionic acid
Documents
$36.65 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-3-chloro-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the fields of medicinal chemistry and biochemistry. Its unique chlorophenyl side chain enhances its reactivity and functional properties, enabling the creation of peptides with specific biological activities.

Researchers and industry professionals appreciate Fmoc-3-chloro-L-phenylalanine for its ability to facilitate the synthesis of complex peptides that can be used in therapeutic applications, such as targeted drug delivery systems and the development of novel pharmaceuticals. Its stability and compatibility with various coupling reagents further enhance its utility in solid-phase peptide synthesis, making it a preferred choice for those looking to streamline their peptide synthesis processes while achieving high yields and purity.

Synonyms
Fmoc-L-Phe(3-Cl)-OH, Fmoc-m-chloro-L-Phe-OH, (S-Fmoc-2-amino-3-(3-chlorophenyl)propionic acid
CAS Number
198560-44-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H20ClNO4
Molecular Weight
421.9
MDL Number
MFCD00672548
PubChem ID
6915685
Melting Point
107 - 126 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -37 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(3-Cl)-OH, Fmoc-m-chloro-L-Phe-OH, (S-Fmoc-2-amino-3-(3-chlorophenyl)propionic acid
CAS Number
198560-44-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H20ClNO4
Molecular Weight
421.9
MDL Number
MFCD00672548
PubChem ID
6915685
Melting Point
107 - 126 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -37 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-chloro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an essential building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, especially in designing peptide-based drugs that can target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The unique properties of this chemical facilitate bioconjugation processes, enabling the attachment of peptides to various biomolecules, which is vital in creating targeted drug delivery systems.
  • Research in Cancer Therapeutics: Its application in the synthesis of peptide analogs has shown promise in developing cancer therapeutics, providing researchers with tools to explore new treatment options.
  • Protein Engineering: This compound is instrumental in modifying proteins to study structure-function relationships, aiding in the design of proteins with enhanced stability and activity for various industrial applications.

Citations