Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
04097
CAS Number:
205526-22-3
Fmoc-2-chloro-D-phenylalanine
Purity:
≥ 98%
Synonym(s):
Fmoc-D-Phe(2-Cl)-OH, Fmoc-o-chloro-D-Phe-OH
Documents
$45.47 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-2-chloro-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective protection of the amino group during the synthesis of peptides. Its chlorinated phenyl side chain enhances the compound's reactivity and allows for the introduction of various functionalities, making it an essential building block in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its stability and compatibility with various coupling reagents, which streamlines the synthesis process and improves yields.

In practical applications, Fmoc-2-chloro-D-phenylalanine is employed in the development of peptide-based therapeutics, particularly in the fields of oncology and immunology. Its ability to form stable peptide bonds while maintaining the integrity of the Fmoc group makes it ideal for solid-phase peptide synthesis. Additionally, its unique properties allow for the exploration of structure-activity relationships in drug design, providing researchers with valuable insights into the pharmacological potential of new compounds. This compound stands out for its efficiency and effectiveness in producing high-quality peptides, making it a preferred choice among professionals in the pharmaceutical and biotechnology industries.

Synonyms
Fmoc-D-Phe(2-Cl)-OH, Fmoc-o-chloro-D-Phe-OH
CAS Number
205526-22-3
Purity
≥ 98%
Molecular Formula
C24H20ClNO4
Molecular Weight
421.9
MDL Number
MFCD00672547
PubChem ID
4199501
Optical Rotation
=+63±2º (c=1, DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Phe(2-Cl)-OH, Fmoc-o-chloro-D-Phe-OH
CAS Number
205526-22-3
Purity
≥ 98%
Molecular Formula
C24H20ClNO4
Molecular Weight
421.9
MDL Number
MFCD00672547
PubChem ID
4199501
Optical Rotation
=+63±2º (c=1, DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-chloro-D-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high efficiency.
  • Drug Development: It plays a significant role in pharmaceutical research, especially in the development of peptide-based drugs, where its unique properties can enhance the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of peptides to various biomolecules, which is essential for creating targeted drug delivery systems.
  • Research in Neuroscience: Its application in neuroscience research aids in studying neuropeptides and their interactions, contributing to a better understanding of neurological disorders.
  • Protein Engineering: The compound is beneficial in protein engineering, where it can be incorporated into proteins to modify their function or stability, thus enhancing their performance in various applications.

Citations