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Catalog Number:
04094
CAS Number:
114873-02-8
Boc-2-chloro-L-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Phe(2-Cl)-OH, Boc-o-chloro-L-Phe-OH, Boc-Phe(2-Cl)-OH
Documents
$29.34 /1G
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Product Information

Boc-2-chloro-L-phenylalanine is a versatile amino acid derivative that serves as a crucial building block in peptide synthesis and drug development. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. Its unique structure, characterized by the presence of a chlorine atom on the phenyl ring, allows for selective modifications, facilitating the design of novel therapeutic agents.

In practical applications, Boc-2-chloro-L-phenylalanine is often utilized in the synthesis of bioactive peptides and pharmaceuticals, particularly those targeting specific biological pathways. Its ability to undergo various coupling reactions makes it a valuable tool for chemists looking to create complex molecular architectures. Additionally, this compound can be employed in the development of inhibitors and modulators for enzyme activity, showcasing its potential in drug discovery and development. Researchers and industry professionals will find Boc-2-chloro-L-phenylalanine to be an essential component in their toolkit for advancing therapeutic innovations.

Synonyms
Boc-L-Phe(2-Cl)-OH, Boc-o-chloro-L-Phe-OH, Boc-Phe(2-Cl)-OH
CAS Number
114873-02-8
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18ClNO4
Molecular Weight
299.8
MDL Number
MFCD00672514
PubChem ID
4398193
Melting Point
77 - 81 °C
Appearance
Off-white powder
Optical Rotation
[a]20D = -23 ± 2 ° (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Phe(2-Cl)-OH, Boc-o-chloro-L-Phe-OH, Boc-Phe(2-Cl)-OH
CAS Number
114873-02-8
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18ClNO4
Molecular Weight
299.8
MDL Number
MFCD00672514
PubChem ID
4398193
Melting Point
77 - 81 °C
Appearance
Off-white powder
Optical Rotation
[a]20D = -23 ± 2 ° (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-2-chloro-L-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of therapeutic proteins and biologically active peptides.
  • Drug Development: It is used in the design of novel pharmaceuticals, especially in creating inhibitors for specific enzymes, which can lead to advancements in treating various diseases.
  • Bioconjugation: The compound can be employed in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents, enhancing their efficacy and targeting capabilities.
  • Research in Neuroscience: Its unique structure makes it a useful tool in studying neurotransmitter systems and receptor interactions, contributing to the understanding of neurological disorders.
  • Custom Synthesis: Laboratories often utilize Boc-2-chloro-L-phenylalanine for custom synthesis projects, providing flexibility in creating tailored compounds for specific research needs.

Citations