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Catalog Number:
04069
CAS Number:
218457-73-9
Fmoc-D-α-aminoadipic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Aad-OH, Fmoc-D-2-aminohexanedioic acid
Documents
$93.14 /250MG
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Product Information

Fmoc-D-a-aminoadipic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it invaluable for researchers in the field of medicinal chemistry. Its unique structure, characterized by a hexanedioic acid backbone, enhances its solubility and reactivity, facilitating the formation of complex peptides with improved biological activity.

In practical applications, Fmoc-D-a-aminoadipic acid is employed in the synthesis of bioactive peptides and pharmaceuticals, particularly in the development of therapeutics targeting various diseases. Its ability to serve as a chiral building block also makes it a preferred choice for researchers aiming to create enantiomerically pure compounds. With its robust performance in peptide coupling reactions, this compound stands out for its efficiency and reliability, making it an essential tool for both academic and industrial laboratories focused on peptide research and development.

Synonyms
Fmoc-D-Aad-OH, Fmoc-D-2-aminohexanedioic acid
CAS Number
218457-73-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.4
MDL Number
MFCD01317727
PubChem ID
23190050
Melting Point
139-147º C
Optical Rotation
=+11.50º ± 1º (c=1.021 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Aad-OH, Fmoc-D-2-aminohexanedioic acid
CAS Number
218457-73-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.4
MDL Number
MFCD01317727
PubChem ID
23190050
Melting Point
139-147º C
Optical Rotation
=+11.50º ± 1º (c=1.021 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-a-aminoadipic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting the overall structure.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, enhancing the stability and bioavailability of drug candidates.
  • Biotechnology: Researchers use it in the development of novel biomaterials, leveraging its properties to create hydrogels and scaffolds for tissue engineering applications.
  • Analytical Chemistry: The compound is utilized in various analytical techniques, including chromatography, to help separate and identify complex mixtures of peptides and proteins.
  • Academic Research: It is frequently employed in laboratories for educational purposes, allowing students and researchers to explore peptide chemistry and its applications in a hands-on manner.

Citations