Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
04062
CAS Number:
42002-05-1
Nα-Boc-L-histidine hydrazide
Purity:
≥ 98% (TLC)
Synonym(s):
Boc-L-His-NHNH2
Documents
$58.39 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Na-Boc-L-histidine hydrazide is a versatile compound widely utilized in the fields of biochemistry and medicinal chemistry. This derivative of histidine features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal candidate for peptide synthesis and drug development. Its unique structure allows for the selective modification of histidine residues in peptides and proteins, facilitating the study of enzyme mechanisms and the development of novel therapeutics. Researchers have leveraged Na-Boc-L-histidine hydrazide in the synthesis of bioactive compounds, including potential inhibitors and ligands, showcasing its relevance in pharmaceutical research.

In addition to its applications in peptide synthesis, Na-Boc-L-histidine hydrazide serves as a valuable building block in the design of targeted drug delivery systems and biomaterials. Its hydrazide functionality can participate in various coupling reactions, enabling the formation of complex molecular architectures. This compound's ability to enhance the pharmacological properties of peptides and its compatibility with various coupling strategies make it a preferred choice for researchers aiming to innovate in drug design and development.

Synonyms
Boc-L-His-NHNH2
CAS Number
42002-05-1
Purity
≥ 98% (TLC)
Molecular Formula
C11H19N5O3
Molecular Weight
269.3
MDL Number
MFCD00055954
PubChem ID
4692013
Melting Point
155 - 157 ?C
Appearance
White product
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-His-NHNH2
CAS Number
42002-05-1
Purity
≥ 98% (TLC)
Molecular Formula
C11H19N5O3
Molecular Weight
269.3
MDL Number
MFCD00055954
PubChem ID
4692013
Melting Point
155 - 157 ?C
Appearance
White product
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-L-histidine hydrazide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly those containing histidine residues, which are crucial for various biological functions.
  • Drug Development: It plays a role in the development of pharmaceuticals, especially in creating compounds that target specific biological pathways, enhancing the efficacy and selectivity of drug candidates.
  • Bioconjugation: The hydrazide functional group allows for efficient bioconjugation techniques, enabling the attachment of drugs or imaging agents to biomolecules, which is essential in targeted therapy and diagnostics.
  • Research in Enzyme Inhibition: Researchers utilize this compound to study enzyme inhibition mechanisms, particularly in the context of histidine-containing enzymes, providing insights into metabolic pathways.
  • Protein Modification: It is used in the modification of proteins to study structure-function relationships, aiding in the understanding of protein interactions and stability.

Citations