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Catalog Number:
04036
Nα-Boc- Nδ-trityl-L-glutamine Merrifield resin
Synonym(s):
Boc-L-Gln(Trt)-Merrifield resin
Documents
$45.47 /1G
Pack Size Availability Price
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Product Information

Na-Boc-Nd-trityl-L-glutamine Merrifield resin is a specialized resin used primarily in peptide synthesis and solid-phase organic chemistry. This compound serves as a versatile building block for the synthesis of peptides, enabling researchers to create complex structures with high specificity and efficiency. Its unique Boc (tert-butyloxycarbonyl) protection group allows for selective deprotection, facilitating the stepwise assembly of peptides while maintaining the integrity of sensitive functional groups. The Nd-trityl modification enhances the stability and solubility of the resin, making it an ideal choice for various applications in pharmaceutical research and development.

This resin is particularly valuable in the production of therapeutic peptides, where precision and purity are paramount. Its application extends to the synthesis of biologically active compounds, including hormones and enzyme inhibitors, which are crucial in drug discovery and development. By utilizing Na-Boc-Nd-trityl-L-glutamine Merrifield resin, researchers can streamline their synthesis processes, reduce reaction times, and achieve higher yields, ultimately accelerating the path from laboratory research to clinical application.

Synonyms
Boc-L-Gln(Trt)-Merrifield resin
MDL Number
MFCD00801361
Substitution
0.25-1.0
Mesh Size
100-200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Boc-L-Gln(Trt)-Merrifield resin
MDL Number
MFCD00801361
Substitution
0.25-1.0
Mesh Size
100-200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc- Nd-trityl-L-glutamine Merrifield resin is widely utilized in research focused on:

  • Peptide Synthesis: This resin serves as a solid support for the synthesis of peptides through the Merrifield method, allowing for efficient and high-yield production of complex peptides.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, facilitating the creation of therapeutic agents with specific biological activity.
  • Bioconjugation: The resin can be used to attach peptides to various biomolecules, enhancing the development of targeted drug delivery systems and improving therapeutic efficacy.
  • Protein Engineering: Researchers utilize this resin in the modification of proteins, enabling the design of novel proteins with desired properties for various applications in biotechnology.
  • Research in Cancer Therapy: By enabling the synthesis of specific peptide sequences, it aids in the development of cancer-targeting agents, potentially leading to more effective treatments.

Citations