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Catalog Number:
04021
CAS Number:
63076-44-8
Boc-L-threonine N-hydroxysuccinimide ester
Purity:
≥ 99% (Elemental Analysis)
Synonym(s):
Boc-L-Thr-OSu
Documents
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Product Information

Boc-L-threonine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This protected amino acid derivative features a Boc (tert-butyloxycarbonyl) group, which provides stability and ease of handling during chemical reactions. Its unique structure allows for selective coupling with various biomolecules, making it an essential tool for researchers in the fields of medicinal chemistry and biotechnology. The N-hydroxysuccinimide (NHS) moiety enhances the reactivity of this compound, facilitating the formation of stable amide bonds with amine-containing substrates, which is crucial for the development of peptide-based therapeutics and targeted drug delivery systems.

In addition to its applications in peptide synthesis, Boc-L-threonine N-hydroxysuccinimide ester is also valuable in the preparation of modified proteins and antibodies, enabling the creation of novel bioconjugates with improved pharmacokinetic properties. Its compatibility with various reaction conditions and ease of purification make it a preferred choice among professionals seeking reliable reagents for complex biochemical applications. With its potential to streamline the synthesis of biologically active compounds, this ester stands out as a key ingredient for advancing research and development in the pharmaceutical industry.

Synonyms
Boc-L-Thr-OSu
CAS Number
63076-44-8
Purity
≥ 99% (Elemental Analysis)
Molecular Formula
C13H20N2O7
Molecular Weight
316.31
MDL Number
MFCD00037904
PubChem ID
99018
Melting Point
133-137 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -32 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Thr-OSu
CAS Number
63076-44-8
Purity
≥ 99% (Elemental Analysis)
Molecular Formula
C13H20N2O7
Molecular Weight
316.31
MDL Number
MFCD00037904
PubChem ID
99018
Melting Point
133-137 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -32 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-threonine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the pharmaceutical industry, where it aids in the development of therapeutic proteins and vaccines.
  • Bioconjugation: It is commonly used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostics and drug delivery systems.
  • Drug Development: The compound plays a crucial role in the design of prodrugs, which improve the solubility and bioavailability of active pharmaceutical ingredients, making them more effective in clinical applications.
  • Research in Protein Engineering: Its application in protein engineering helps in modifying proteins to study their functions or improve their properties, which is essential in biotechnology and enzyme development.
  • Diagnostic Applications: The ester is utilized in the development of diagnostic assays, where it can improve the specificity and sensitivity of tests, benefiting fields like medical diagnostics and environmental monitoring.

Citations