Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
03993
CAS Number:
3350-19-4
Boc-L-leucine 4-nitrophenyl ester
Purity:
≥ 97% (HPLC)
Synonym(s):
Boc-L-Leu-ONp, (S)-Boc-2-amino-4-methyl-pentanoic acid 4-nitrophenylester
Documents
$22.83 /5G
Pack Size Availability Price
Request Bulk Quote
Product Information

Boc-L-leucine 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This compound serves as a protective group for amino acids, particularly in the formation of peptide bonds, facilitating the synthesis of complex peptides and proteins. Its unique structure allows for selective reactions, making it an essential tool for researchers aiming to develop new therapeutic agents or study protein interactions. The presence of the 4-nitrophenyl group enhances its reactivity, providing researchers with a reliable method for the introduction of leucine residues into peptides, which are crucial for various biological functions.

In addition to its role in peptide synthesis, Boc-L-leucine 4-nitrophenyl ester is also valuable in the development of drug delivery systems and bioconjugates. Its stability and ease of handling make it an attractive choice for both academic and industrial applications. Researchers appreciate its ability to improve the solubility and bioavailability of peptides, ultimately leading to more effective therapeutic outcomes. With its broad range of applications, this compound is a must-have for any laboratory focused on peptide chemistry and drug development.

Synonyms
Boc-L-Leu-ONp, (S)-Boc-2-amino-4-methyl-pentanoic acid 4-nitrophenylester
CAS Number
3350-19-4
Purity
≥ 97% (HPLC)
Molecular Formula
C17H24N2O6
Molecular Weight
352.39
MDL Number
MFCD00038291
PubChem ID
102988
Melting Point
71-77º C
Optical Rotation
-41.0º ± 1º (c=1.028% DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Leu-ONp, (S)-Boc-2-amino-4-methyl-pentanoic acid 4-nitrophenylester
CAS Number
3350-19-4
Purity
≥ 97% (HPLC)
Molecular Formula
C17H24N2O6
Molecular Weight
352.39
MDL Number
MFCD00038291
PubChem ID
102988
Melting Point
71-77º C
Optical Rotation
-41.0º ± 1º (c=1.028% DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-leucine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, enhancing the efficiency of coupling reactions.
  • Drug Development: It is used in the design of prodrugs, which can improve the bioavailability of therapeutic agents by modifying their solubility and absorption characteristics.
  • Bioconjugation: The compound facilitates the attachment of biomolecules to surfaces or other molecules, which is crucial in developing targeted drug delivery systems.
  • Research in Enzyme Inhibition: It acts as a substrate or inhibitor in enzyme studies, helping researchers understand enzyme mechanisms and develop new inhibitors.
  • Analytical Chemistry: Boc-L-leucine 4-nitrophenyl ester is employed in chromatography and mass spectrometry, aiding in the separation and identification of complex mixtures.

Citations