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Catalog Number:
03992
CAS Number:
16948-38-2
Boc-L-isoleucine 4-nitrophenyl ester
Purity:
≥ 98% (TLC)
Synonym(s):
Boc-L-Ile-ONp
Documents
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Product Information

Boc-L-isoleucine 4-nitrophenyl ester is a valuable compound widely utilized in peptide synthesis and medicinal chemistry. This derivative of isoleucine features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for researchers working on complex peptide sequences. The presence of the 4-nitrophenyl ester moiety not only facilitates the coupling reactions but also allows for easy monitoring of reaction progress through UV spectroscopy, providing a significant advantage in synthetic protocols.

In pharmaceutical research, Boc-L-isoleucine 4-nitrophenyl ester serves as a key intermediate in the development of bioactive peptides and therapeutic agents. Its unique properties enable the formation of diverse peptide structures, which are essential in drug discovery and development. Researchers appreciate its compatibility with various coupling reagents and its ability to yield high-purity products, making it a preferred choice in laboratories focused on peptide-based therapeutics.

Synonyms
Boc-L-Ile-ONp
CAS Number
16948-38-2
Purity
≥ 98% (TLC)
Molecular Formula
C17H24N2O6
Molecular Weight
352.39
MDL Number
MFCD00038322
PubChem ID
86096
Melting Point
62-72 ?C
Optical Rotation
[a]D24 = -33 ± 2º (C=2 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Ile-ONp
CAS Number
16948-38-2
Purity
≥ 98% (TLC)
Molecular Formula
C17H24N2O6
Molecular Weight
352.39
MDL Number
MFCD00038322
PubChem ID
86096
Melting Point
62-72 ?C
Optical Rotation
[a]D24 = -33 ± 2º (C=2 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-isoleucine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing researchers to create complex structures with specific amino acid sequences.
  • Drug Development: Its application in medicinal chemistry facilitates the design of novel pharmaceuticals, particularly in targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Research in Protein Engineering: It plays a crucial role in modifying proteins, aiding in the development of proteins with improved stability and functionality for various industrial applications.
  • Analytical Chemistry: The compound is employed in analytical methods to study the properties of amino acids and peptides, providing insights into their behavior in different environments.

Citations