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Catalog Number:
03950
CAS Number:
173054-11-0
Boc-4-(Fmoc-amino)-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-D-Phe(4-NH-Fmoc)-OH, Boc-p-(Fmoc-amino)-D-Phe-OH, (R-Boc-2-amino-3-(4-Fmoc-aminophenyl)propionoic acid
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Product Information

Boc-4-(Fmoc-amino)-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a unique combination of protective groups, specifically the Boc (tert-butyloxycarbonyl) and Fmoc (9-fluorenylmethoxycarbonyl) moieties, which facilitate the selective protection of amino groups during the synthesis of complex peptides. Its structural characteristics make it an ideal choice for researchers looking to create stable and functional peptide sequences, particularly in the development of therapeutic agents and bioconjugates.

In addition to its role in peptide synthesis, Boc-4-(Fmoc-amino)-D-phenylalanine is also valuable in the study of protein interactions and drug design. Its ability to mimic natural amino acids while providing enhanced stability and solubility makes it a preferred option for scientists aiming to optimize the pharmacokinetic properties of their compounds. With its broad applicability in medicinal chemistry and biochemistry, this compound stands out as a crucial building block for innovative research and development in the life sciences.

Synonyms
Boc-D-Phe(4-NH-Fmoc)-OH, Boc-p-(Fmoc-amino)-D-Phe-OH, (R-Boc-2-amino-3-(4-Fmoc-aminophenyl)propionoic acid
CAS Number
173054-11-0
Purity
≥ 98% (HPLC)
Molecular Formula
C29H30N2O6
Molecular Weight
502.56
MDL Number
MFCD00151888
PubChem ID
4712502
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-D-Phe(4-NH-Fmoc)-OH, Boc-p-(Fmoc-amino)-D-Phe-OH, (R-Boc-2-amino-3-(4-Fmoc-aminophenyl)propionoic acid
CAS Number
173054-11-0
Purity
≥ 98% (HPLC)
Molecular Formula
C29H30N2O6
Molecular Weight
502.56
MDL Number
MFCD00151888
PubChem ID
4712502
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-(Fmoc-amino)-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: It plays a significant role in the development of pharmaceutical compounds, especially in designing peptide-based drugs that can target specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach peptides to various biomolecules, enhancing the delivery and efficacy of therapeutic agents.
  • Research in Neuroscience: It is applied in studies related to neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.
  • Protein Engineering: This compound is valuable in protein engineering, facilitating the modification of proteins to improve their stability and functionality for various industrial applications.

Citations