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Catalog Number:
03913
CAS Number:
139551-73-8
Fmoc-S-benzyl-D-penicillamine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Pen(Bzl)-OH, Fmoc-S-benzyl-β,β-dimethyl-D-Cys-OH
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Product Information

Fmoc-S-benzyl-D-penicillamine is a versatile compound widely utilized in peptide synthesis and drug development. This thiol-containing amino acid derivative is particularly valued for its ability to form stable disulfide bonds, making it an essential building block in the creation of peptide-based therapeutics. Its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection under mild conditions, facilitating the synthesis of complex peptides with high purity and yield. Researchers in medicinal chemistry and biochemistry often employ this compound to explore novel drug candidates, especially in the development of inhibitors and modulators for various biological targets.

In addition to its applications in peptide synthesis, Fmoc-S-benzyl-D-penicillamine has shown potential in the field of materials science, where it can be used to create functionalized surfaces and nanomaterials. Its ability to interact with metal ions also opens avenues for applications in catalysis and sensor technology. With its robust chemical properties and adaptability, this compound stands out as a valuable asset for researchers and industry professionals seeking innovative solutions in drug discovery and materials engineering.

Synonyms
Fmoc-D-Pen(Bzl)-OH, Fmoc-S-benzyl-β,β-dimethyl-D-Cys-OH
CAS Number
139551-73-8
Purity
≥ 98% (HPLC)
Molecular Formula
C27H27NO4S
Molecular Weight
461.58
MDL Number
MFCD00151936
PubChem ID
19978416
Melting Point
54 - 66 °C
Optical Rotation
[a]20D
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Pen(Bzl)-OH, Fmoc-S-benzyl-β,β-dimethyl-D-Cys-OH
CAS Number
139551-73-8
Purity
≥ 98% (HPLC)
Molecular Formula
C27H27NO4S
Molecular Weight
461.58
MDL Number
MFCD00151936
PubChem ID
19978416
Melting Point
54 - 66 °C
Optical Rotation
[a]20D
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-benzyl-D-penicillamine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for creating complex peptides used in pharmaceuticals.
  • Drug Development: Its unique structure makes it valuable in the design of novel drugs, particularly in targeting specific biological pathways. Researchers leverage its properties to enhance the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The compound is employed in bioconjugation techniques, where it aids in attaching biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and drug delivery systems.
  • Research in Neuroscience: It is used in studies related to neurochemistry, particularly in the development of compounds that can cross the blood-brain barrier, which is essential for treating neurological disorders.
  • Antioxidant Studies: Researchers explore its antioxidant properties, which can lead to the development of new therapeutic strategies for diseases related to oxidative stress.

Citations