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Catalog Number:
03867
CAS Number:
4467-55-4
Z-D-valine N-hydroxysuccinimide ester
Purity:
99%
Synonym(s):
Z-D-Val-OSu
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Product Information

Z-D-valine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound serves as an effective coupling agent, facilitating the formation of peptide bonds and enhancing the efficiency of solid-phase peptide synthesis. Its unique structure allows for selective reactions, making it an ideal choice for researchers aiming to develop complex peptides with high purity and yield. The N-hydroxysuccinimide moiety provides stability and reactivity, enabling the formation of stable amide bonds with various amino acids and other nucleophiles.

In addition to its role in peptide synthesis, Z-D-valine N-hydroxysuccinimide ester is also valuable in the pharmaceutical industry for drug development and delivery systems. Its ability to form conjugates with therapeutic agents enhances bioavailability and targeted delivery, making it a crucial component in the design of novel drug formulations. Researchers and industry professionals can leverage this compound to streamline their synthesis processes and improve the efficacy of their products, ultimately leading to advancements in therapeutic applications.

Synonyms
Z-D-Val-OSu
CAS Number
4467-55-4
Purity
99%
Molecular Formula
C17H20N2O6
Molecular Weight
348.4
MDL Number
MFCD00153351
PubChem ID
100051
Melting Point
108 - 113 °C
Appearance
White to off-white solid
Optical Rotation
[a]20D = 18 ± 1 º ( C=1.157 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Z-D-Val-OSu
CAS Number
4467-55-4
Purity
99%
Molecular Formula
C17H20N2O6
Molecular Weight
348.4
MDL Number
MFCD00153351
PubChem ID
100051
Melting Point
108 - 113 °C
Appearance
White to off-white solid
Optical Rotation
[a]20D = 18 ± 1 º ( C=1.157 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-D-valine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing for the incorporation of Z-D-valine into peptide chains, which can enhance their stability and bioactivity.
  • Drug Development: It is used in the pharmaceutical industry to create prodrugs, which can improve the solubility and absorption of active pharmaceutical ingredients, leading to more effective medications.
  • Bioconjugation: The compound facilitates the conjugation of biomolecules, such as antibodies or enzymes, to various carriers, enhancing their therapeutic efficacy and targeting capabilities in drug delivery systems.
  • Research in Protein Engineering: Scientists utilize this ester to modify proteins, allowing for the exploration of structure-function relationships and the development of novel protein-based therapeutics.
  • Diagnostic Applications: It can be employed in the development of diagnostic assays, where the modification of biomolecules improves the sensitivity and specificity of detection methods.

Citations