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Catalog Number:
03859
CAS Number:
76401-90-6
Z-L-threonine N-hydroxysuccinimide ester
Purity:
≥ 90% (TLC)
Synonym(s):
Z-L-Thr-OSu
Documents
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Product Information

Z-L-threonine N-hydroxysuccinimide ester is a versatile compound widely utilized in biochemical research and pharmaceutical applications. This ester derivative of threonine is particularly valuable for its role in peptide synthesis and as a building block in the development of bioactive molecules. Its unique structure enhances solubility and stability, making it an excellent choice for researchers looking to create complex peptides with improved pharmacological properties.

In the pharmaceutical industry, Z-L-threonine N-hydroxysuccinimide ester is often employed in the design of drug delivery systems and targeted therapies, where its ability to form stable conjugates with various biomolecules can lead to enhanced efficacy and reduced side effects. Additionally, its utility in the synthesis of peptide-based therapeutics positions it as a critical component in the development of novel treatments for a range of diseases. Researchers and industry professionals can leverage this compound's properties to innovate and improve existing therapeutic strategies.

Synonyms
Z-L-Thr-OSu
CAS Number
76401-90-6
Purity
≥ 90% (TLC)
Molecular Formula
C16H18N2O7
Molecular Weight
350.3
MDL Number
MFCD00153344
PubChem ID
13890411
Melting Point
98 - 100 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -31 ± 2 º (C=2 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Z-L-Thr-OSu
CAS Number
76401-90-6
Purity
≥ 90% (TLC)
Molecular Formula
C16H18N2O7
Molecular Weight
350.3
MDL Number
MFCD00153344
PubChem ID
13890411
Melting Point
98 - 100 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -31 ± 2 º (C=2 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-threonine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Bioconjugation: It is often used in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutic agents.
  • Drug Delivery Systems: The ester form aids in the development of drug delivery systems, improving the solubility and stability of pharmaceutical compounds, which is crucial for effective treatment.
  • Research in Protein Engineering: This compound is instrumental in protein engineering, enabling scientists to modify proteins for better performance in therapeutic applications or industrial processes.
  • Development of Antibody-Drug Conjugates: It plays a key role in the creation of antibody-drug conjugates, which are designed for targeted cancer therapies, providing a more effective treatment option with reduced side effects.

Citations