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Catalog Number:
03849
CAS Number:
15545-10-5
Nα-Z-L-histidine methyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Z-L-His-OMe
Documents
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Product Information

Na-Z-L-histidine methyl ester is a versatile compound widely recognized for its applications in biochemistry and pharmaceuticals. This derivative of histidine, an essential amino acid, serves as a valuable building block in peptide synthesis and drug development. Its unique structure allows for enhanced solubility and bioavailability, making it an ideal candidate for formulating therapeutic agents. Researchers often utilize Na-Z-L-histidine methyl ester in the development of enzyme inhibitors and as a substrate in various biochemical assays, facilitating advancements in drug discovery and metabolic studies.

In addition to its role in research, this compound is also employed in the synthesis of complex molecules, including those used in the treatment of neurological disorders and cancer. Its ability to mimic natural substrates enhances its utility in medicinal chemistry, providing a pathway for the design of novel therapeutics. With its favorable properties and broad applicability, Na-Z-L-histidine methyl ester stands out as a crucial component in the toolkit of researchers and industry professionals focused on innovative solutions in health and medicine.

Synonyms
Z-L-His-OMe
CAS Number
15545-10-5
Purity
≥ 99% (HPLC)
Molecular Formula
C15H17N3O4
Molecular Weight
303.3
MDL Number
MFCD00153333
PubChem ID
13918734
Melting Point
105-110 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -17 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Z-L-His-OMe
CAS Number
15545-10-5
Purity
≥ 99% (HPLC)
Molecular Formula
C15H17N3O4
Molecular Weight
303.3
MDL Number
MFCD00153333
PubChem ID
13918734
Melting Point
105-110 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -17 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Z-L-histidine methyl ester is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is often used as a building block in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders due to its histidine structure, which plays a role in neurotransmitter function.
  • Biochemical Research: It serves as a substrate in enzyme assays, helping researchers study the kinetics of histidine-related enzymes, which are crucial in metabolic pathways.
  • Protein Engineering: The compound is employed in the modification of peptides and proteins, enhancing their stability and activity, which is vital for therapeutic applications.
  • Antioxidant Studies: Na-Z-L-histidine methyl ester is investigated for its potential antioxidant properties, making it relevant in studies aimed at combating oxidative stress in cells.
  • Drug Delivery Systems: Its unique chemical properties allow it to be used in the formulation of drug delivery systems, improving the bioavailability of certain medications.

Citations