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Catalog Number:
03833
CAS Number:
132160-73-7
Nα,Nω,Nω-Tris-Z-L-arginine N-hydroxysuccinimide ester
Purity:
≥ 98% (TLC)
Synonym(s):
Z-L-Arg(Z)2-OSu
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Product Information

Na,Nw,Nw'-Tris-Z-L-arginine N-hydroxysuccinimide ester is a versatile compound widely utilized in biochemistry and pharmaceutical research. This derivative of L-arginine is particularly valued for its ability to facilitate peptide synthesis and conjugation reactions, making it an essential tool for researchers working on drug development and protein engineering. Its unique structure allows for enhanced solubility and stability, which are critical factors in biological applications. The compound's N-hydroxysuccinimide ester functionality enables efficient coupling with various biomolecules, including peptides and proteins, thereby streamlining the process of creating complex bioconjugates.

In practical applications, Na,Nw,Nw'-Tris-Z-L-arginine N-hydroxysuccinimide ester is often employed in the development of targeted drug delivery systems and in the design of novel therapeutics. Its ability to form stable linkages with biomolecules makes it an attractive choice for researchers aiming to improve the efficacy and specificity of their drug candidates. Additionally, this compound's favorable properties position it as a superior alternative to other coupling agents, offering enhanced reaction rates and reduced side reactions, which can significantly improve overall yield and purity in synthetic processes.

Synonyms
Z-L-Arg(Z)2-OSu
CAS Number
132160-73-7
Purity
≥ 98% (TLC)
Molecular Formula
C34H35N5O10
Molecular Weight
673.7
MDL Number
MFCD06795825
PubChem ID
13819632
Melting Point
85-93 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -10 ± 2º (C=2 in Dioxane)
Conditions
Store at 0-8 °C
General Information
Synonyms
Z-L-Arg(Z)2-OSu
CAS Number
132160-73-7
Purity
≥ 98% (TLC)
Molecular Formula
C34H35N5O10
Molecular Weight
673.7
MDL Number
MFCD06795825
PubChem ID
13819632
Melting Point
85-93 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -10 ± 2º (C=2 in Dioxane)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na,Nw,Nw'-Tris-Z-L-arginine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile linker in bioconjugation processes, allowing researchers to attach biomolecules like proteins or antibodies to surfaces or other molecules, enhancing the development of targeted therapies.
  • Drug Delivery Systems: Its ability to form stable complexes with drugs makes it valuable in the design of drug delivery systems, improving the bioavailability and efficacy of therapeutic agents in pharmaceutical applications.
  • Peptide Synthesis: This chemical is instrumental in peptide synthesis, facilitating the formation of complex peptides with specific functionalities, which are crucial in developing new drugs and vaccines.
  • Diagnostics: It is used in diagnostic kits for the detection of various diseases, enabling the development of sensitive assays that can identify biomarkers with high specificity.
  • Research in Cancer Therapy: The compound is being explored in cancer research for its potential to enhance the delivery of chemotherapeutic agents directly to tumor sites, thereby reducing side effects and improving treatment outcomes.

Citations