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Catalog Number:
03830
CAS Number:
74844-93-2
Boc-3,4-dehydro-L-proline methyl ester
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-3,4-dehydro-L-Pro-OMe, (S)-Boc-3,4-dehydro-pyrrolidine methyl ester
Documents
$127.80 /100MG
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Product Information

Boc-3,4-dehydro-L-proline methyl ester is a versatile compound widely utilized in the field of organic synthesis and pharmaceutical research. This compound serves as a valuable building block in the synthesis of various bioactive molecules, particularly in the development of peptide-based therapeutics. Its unique structure, featuring a tert-butyl protecting group, enhances its stability and reactivity, making it an ideal candidate for applications in medicinal chemistry. Researchers appreciate its role in facilitating the formation of complex molecular architectures, which are essential in drug discovery and development.

In addition to its synthetic utility, Boc-3,4-dehydro-L-proline methyl ester has shown promise in the design of novel inhibitors and biologically active compounds. Its ability to mimic natural amino acids allows for the exploration of new therapeutic avenues, particularly in the treatment of diseases where peptide modulation is beneficial. The compound's favorable properties, such as ease of handling and compatibility with various reaction conditions, further solidify its position as a go-to reagent for chemists and researchers aiming to innovate in the pharmaceutical landscape.

Synonyms
Boc-3,4-dehydro-L-Pro-OMe, (S)-Boc-3,4-dehydro-pyrrolidine methyl ester
CAS Number
74844-93-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C11H17NO4
Molecular Weight
227.23
MDL Number
MFCD00080341
PubChem ID
9815988
Appearance
Light yellowish liquid
Optical Rotation
[a]25D = 261 ± 2 ° (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-3,4-dehydro-L-Pro-OMe, (S)-Boc-3,4-dehydro-pyrrolidine methyl ester
CAS Number
74844-93-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C11H17NO4
Molecular Weight
227.23
MDL Number
MFCD00080341
PubChem ID
9815988
Appearance
Light yellowish liquid
Optical Rotation
[a]25D = 261 ± 2 ° (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3,4-dehydro-L-proline methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of cyclic peptides that have enhanced stability and bioactivity.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for designing novel drug candidates, especially in the creation of compounds targeting specific biological pathways.
  • Bioconjugation: Researchers use it to facilitate bioconjugation processes, allowing for the attachment of biomolecules to therapeutic agents, which can improve drug delivery and efficacy.
  • Protein Engineering: This chemical is employed in modifying proteins to enhance their properties, such as solubility and stability, which is essential for therapeutic applications.
  • Research in Neuroscience: It is used in studies related to neurotransmitter systems, aiding in the understanding of neurological pathways and potential treatments for neurodegenerative diseases.

Citations