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Catalog Number:
03818
CAS Number:
20866-56-2
Boc-L-tyrosine N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Tyr-OSu
Documents
$29.34 /1G
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Product Information

Boc-L-tyrosine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This derivative of L-tyrosine features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal choice for researchers looking to incorporate tyrosine into peptides or proteins without compromising their integrity. The N-hydroxysuccinimide (NHS) moiety facilitates efficient coupling reactions, allowing for the formation of stable amide bonds with various nucleophiles, including amino acids and proteins.

This compound is particularly valuable in the fields of drug development and biomolecular research, where precise modifications of peptides are essential for creating therapeutic agents or studying protein interactions. Its ability to selectively react with amines while maintaining the integrity of the tyrosine side chain opens up numerous possibilities for designing novel biomolecules. Researchers appreciate its ease of use and the high yield of reactions, making Boc-L-tyrosine N-hydroxysuccinimide ester a preferred choice for advancing peptide chemistry.

Synonyms
Boc-L-Tyr-OSu
CAS Number
20866-56-2
Purity
≥ 98% (HPLC)
Molecular Formula
C18H22N2O7
Molecular Weight
378.4
MDL Number
MFCD00037910
PubChem ID
333430
Appearance
White powder
Optical Rotation
-13±1° (c= 1% dioxane)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Tyr-OSu
CAS Number
20866-56-2
Purity
≥ 98% (HPLC)
Molecular Formula
C18H22N2O7
Molecular Weight
378.4
MDL Number
MFCD00037910
PubChem ID
333430
Appearance
White powder
Optical Rotation
-13±1° (c= 1% dioxane)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-tyrosine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities, enhancing the development of therapeutic agents.
  • Drug Development: Its ability to modify amino acids makes it valuable in drug design, particularly in creating prodrugs that improve the bioavailability of active pharmaceutical ingredients.
  • Bioconjugation: The ester functionality facilitates the conjugation of biomolecules, which is crucial in developing targeted drug delivery systems and diagnostic tools in the biomedical field.
  • Research in Neuroscience: As a derivative of tyrosine, it plays a role in studying neurotransmitter pathways, aiding in the understanding of various neurological conditions and potential treatments.
  • Protein Engineering: It is used to introduce specific modifications in proteins, enhancing their stability and activity, which is essential for various applications in biotechnology and pharmaceuticals.

Citations