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Catalog Number:
03817
CAS Number:
144599-95-1
Nα-Boc-Nin-Boc-L-tryptophan
Purity:
≥ 99.0% (HPLC)
Synonym(s):
Boc-L-Trp(Boc)-OH
Documents
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Product Information

Na-Boc-Nin-Boc-L-tryptophan is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features two Boc (tert-butyloxycarbonyl) protecting groups, which enhance its stability and reactivity, making it an ideal choice for researchers and professionals in the fields of medicinal chemistry and biochemistry. Its unique structure allows for selective reactions, facilitating the synthesis of complex peptides and proteins.

In practical applications, Na-Boc-Nin-Boc-L-tryptophan is particularly valuable in the development of pharmaceuticals targeting neurological disorders, as tryptophan is a precursor to serotonin. Additionally, its use in combinatorial chemistry and peptide libraries enables the exploration of novel therapeutic agents. With its favorable properties and broad applicability, this compound stands out as a key building block for innovative research and development in the life sciences.

Synonyms
Boc-L-Trp(Boc)-OH
CAS Number
144599-95-1
Purity
≥ 99.0% (HPLC)
Molecular Formula
C21H28N2O6
Molecular Weight
404.46
MDL Number
MFCD00270520
PubChem ID
53442664
Melting Point
155-165°C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 10.5 ± 2° (C=3 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Trp(Boc)-OH
CAS Number
144599-95-1
Purity
≥ 99.0% (HPLC)
Molecular Formula
C21H28N2O6
Molecular Weight
404.46
MDL Number
MFCD00270520
PubChem ID
53442664
Melting Point
155-165°C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 10.5 ± 2° (C=3 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nin-Boc-L-tryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly for those requiring protected amino acids. Its Boc (tert-butoxycarbonyl) groups provide stability during the synthesis process.
  • Drug Development: Researchers leverage its properties to develop novel pharmaceuticals, especially in the field of neuropharmacology, where tryptophan derivatives play a crucial role in serotonin production.
  • Bioconjugation: The compound is used in bioconjugation techniques, allowing for the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: Its application in studies related to neurotransmitter pathways helps scientists understand mood regulation and the impact of tryptophan on mental health.
  • Protein Engineering: This compound aids in the design of proteins with specific functionalities, enhancing the development of enzymes and therapeutic proteins in biotechnology.

Citations