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Catalog Number:
03811
CAS Number:
102185-34-2
Boc-D-proline N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-D-Pro-OSu
Documents
$29.34 /1G
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Product Information

Boc-D-proline N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound serves as a valuable building block for the creation of peptide chains, particularly in the formation of proline-containing peptides, which are essential in various biological processes. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers focusing on the development of novel therapeutics and biologically active compounds. The N-hydroxysuccinimide moiety enhances the reactivity of the ester, facilitating smoother and more efficient reactions compared to traditional coupling agents.

In addition to its role in peptide synthesis, Boc-D-proline N-hydroxysuccinimide ester is also employed in the modification of biomolecules, enabling the introduction of specific functionalities that can enhance the pharmacological properties of drugs. Its stability and ease of use make it a preferred choice for both academic and industrial applications. Researchers can leverage this compound to streamline their synthesis processes, ultimately leading to more efficient drug discovery and development.

Synonyms
Boc-D-Pro-OSu
CAS Number
102185-34-2
Purity
≥ 98% (HPLC)
Molecular Formula
C14H20N2O6
Molecular Weight
312.3
MDL Number
MFCD00069687
PubChem ID
102995
Melting Point
132-137 °C
Appearance
White powder
Optical Rotation
[a]D20 = +57 ± 2º (C=1 in Dioxane)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-D-Pro-OSu
CAS Number
102185-34-2
Purity
≥ 98% (HPLC)
Molecular Formula
C14H20N2O6
Molecular Weight
312.3
MDL Number
MFCD00069687
PubChem ID
102995
Melting Point
132-137 °C
Appearance
White powder
Optical Rotation
[a]D20 = +57 ± 2º (C=1 in Dioxane)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-proline N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing for the incorporation of D-proline, which can enhance the stability and bioactivity of the resulting peptides.
  • Drug Development: In pharmaceutical research, it is used to create proline-containing compounds that can lead to novel therapeutics, particularly in the treatment of various diseases where proline plays a critical role.
  • Bioconjugation: The N-hydroxysuccinimide group facilitates the conjugation of biomolecules, making it ideal for creating targeted drug delivery systems or labeling proteins for imaging applications.
  • Protein Engineering: Researchers leverage this compound to modify proteins, enhancing their properties for specific applications in biotechnology and medicine, such as improving enzyme activity or stability.
  • Research in Structural Biology: It aids in the study of protein folding and interactions, providing insights into the structural dynamics of proteins that are crucial for understanding biological processes.

Citations