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Catalog Number:
03810
CAS Number:
28310-65-8
Boc-L-proline 4-nitrophenyl ester
Purity:
≥ 99% (TLC)
Synonym(s):
Boc-L-Pro-ONp, (S-Boc-pyrrolidine-2-carboxylic acid 4-nitrophenyl ester
Documents
$40.30 /1G
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Product Information

Boc-L-proline 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This protected amino acid derivative features a tert-butyl group that enhances its stability and solubility, making it an ideal choice for researchers looking to streamline their synthesis processes. Its unique structure allows for selective reactions, facilitating the development of complex peptides and biologically active compounds.

In the pharmaceutical industry, Boc-L-proline 4-nitrophenyl ester serves as a key intermediate in the production of various therapeutic agents, particularly those targeting neurological disorders and cancer. Its ability to undergo specific transformations while maintaining structural integrity makes it a valuable tool for chemists aiming to create novel drug candidates. Additionally, its application in solid-phase peptide synthesis highlights its importance in the development of peptide-based therapeutics. With its favorable properties and practical applications, Boc-L-proline 4-nitrophenyl ester stands out as a crucial component for researchers and industry professionals alike.

Synonyms
Boc-L-Pro-ONp, (S-Boc-pyrrolidine-2-carboxylic acid 4-nitrophenyl ester
CAS Number
28310-65-8
Purity
≥ 99% (TLC)
Molecular Formula
C16H20N2O6
Molecular Weight
336.3
MDL Number
MFCD00037323
PubChem ID
294906
Melting Point
58-66 ºC
Appearance
Pale beige powder
Optical Rotation
[a]D24 = -53 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Pro-ONp, (S-Boc-pyrrolidine-2-carboxylic acid 4-nitrophenyl ester
CAS Number
28310-65-8
Purity
≥ 99% (TLC)
Molecular Formula
C16H20N2O6
Molecular Weight
336.3
MDL Number
MFCD00037323
PubChem ID
294906
Melting Point
58-66 ºC
Appearance
Pale beige powder
Optical Rotation
[a]D24 = -53 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-proline 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active molecules.
  • Drug Development: Its unique structure allows for modifications that can enhance the efficacy and selectivity of drug candidates, making it valuable in medicinal chemistry.
  • Bioconjugation: The ester functionality enables easy conjugation with various biomolecules, facilitating the creation of targeted drug delivery systems.
  • Research in Enzyme Inhibition: It is used in studies aimed at understanding enzyme mechanisms, providing insights that can lead to the development of new inhibitors.
  • Material Science: This compound can be incorporated into polymers, enhancing their properties for applications in coatings and adhesives.

Citations