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Catalog Number:
03761
CAS Number:
608512-85-2
Fmoc-L-aspartic acid ॆ-9-fluorenylmethyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Asp(OFm)-OH
Documents
$134.70 /1G
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Product Information

Fmoc-L-aspartic acid b-9-fluorenylmethyl ester is a versatile and valuable compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability and facilitates the selective deprotection of the amino group during solid-phase peptide synthesis (SPPS). Its unique structure enhances the efficiency of synthesizing complex peptides, making it an essential reagent for researchers in the fields of biochemistry and medicinal chemistry.

In addition to its role in peptide synthesis, Fmoc-L-aspartic acid b-9-fluorenylmethyl ester is also employed in the development of peptide-based therapeutics and biomaterials. Its ability to form stable linkages and its compatibility with various coupling reagents allow for the creation of diverse peptide sequences, which can be tailored for specific biological activities. This compound stands out for its ease of use and effectiveness, making it a preferred choice for professionals seeking reliable results in their research and applications.

Synonyms
Fmoc-L-Asp(OFm)-OH
CAS Number
608512-85-2
Purity
≥ 98% (HPLC)
Molecular Formula
C33H27NO6
Molecular Weight
491.3
MDL Number
MFCD01631977
PubChem ID
137796129
Appearance
White powder
Optical Rotation
[a]D20 = -3 ± 1º (C=0.5 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Asp(OFm)-OH
CAS Number
608512-85-2
Purity
≥ 98% (HPLC)
Molecular Formula
C33H27NO6
Molecular Weight
491.3
MDL Number
MFCD01631977
PubChem ID
137796129
Appearance
White powder
Optical Rotation
[a]D20 = -3 ± 1º (C=0.5 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-aspartic acid b-9-fluorenylmethyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), where its protective group facilitates the sequential addition of amino acids.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, enhancing the stability and bioavailability of therapeutic compounds.
  • Bioconjugation: The b-9-fluorenylmethyl ester group allows for selective conjugation with other biomolecules, making it useful in creating targeted drug delivery systems.
  • Research in Neuroscience: This compound is utilized in studies related to neurotransmitter pathways, particularly in the synthesis of aspartate derivatives that can influence neuronal signaling.
  • Material Science: It is also explored in the development of novel materials, such as hydrogels, that can be used in biomedical applications due to its biocompatibility and functional properties.

Citations