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Catalog Number:
03746
CAS Number:
191348-16-0
Fmoc-O-benzylphospho-L-tyrosine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Tyr(HPO3Bzl)-OH
Documents
$108.26 /250MG
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Product Information

Fmoc-O-benzylphospho-L-tyrosine is a versatile phosphotyrosine derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound is particularly valued in the fields of medicinal chemistry and biochemistry for its ability to mimic phosphorylated tyrosine residues, which are essential in various cellular signaling pathways. Researchers utilize Fmoc-O-benzylphospho-L-tyrosine to study protein interactions and enzyme activities, making it an indispensable tool for drug discovery and development. Its unique Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for straightforward incorporation into peptides, facilitating the synthesis of complex biomolecules.

Moreover, this compound's stability and solubility in organic solvents enhance its usability in various experimental conditions, providing researchers with reliable results. Fmoc-O-benzylphospho-L-tyrosine is also advantageous for developing targeted therapies, as it can be used to create phosphopeptide libraries that aid in the identification of novel therapeutic targets. Its application in the synthesis of phosphopeptides not only streamlines research but also opens avenues for innovative treatments in cancer and other diseases.

Synonyms
Fmoc-L-Tyr(HPO3Bzl)-OH
CAS Number
191348-16-0
Purity
≥ 97% (HPLC)
Molecular Formula
C31H28NO8P
Molecular Weight
573.5
MDL Number
MFCD00797871
PubChem ID
75210600
Melting Point
131 - 165 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -15 ± 2 º (C=2 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Tyr(HPO3Bzl)-OH
CAS Number
191348-16-0
Purity
≥ 97% (HPLC)
Molecular Formula
C31H28NO8P
Molecular Weight
573.5
MDL Number
MFCD00797871
PubChem ID
75210600
Melting Point
131 - 165 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -15 ± 2 º (C=2 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-benzylphospho-L-tyrosine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of phosphopeptides, which are vital for studying protein interactions and signaling pathways.
  • Drug Development: Its role in drug design allows researchers to create targeted therapies that mimic natural phosphoproteins, enhancing the specificity and efficacy of treatments.
  • Bioconjugation: The compound is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, facilitating the development of biosensors and diagnostic tools.
  • Research in Cancer Biology: By studying the interactions of phosphopeptides containing this compound, scientists can gain insights into cancer cell signaling, potentially leading to new therapeutic strategies.
  • Analytical Chemistry: It is employed in various analytical techniques, such as mass spectrometry, to help identify and quantify phosphoproteins, contributing to a better understanding of cellular processes.

Citations