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Catalog Number:
03736
CAS Number:
158000-21-6
Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester
Documents
$36.65 /1G
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Product Information

Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester is a versatile and valuable compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc group that facilitates the selective coupling of amino acids, making it an essential reagent for researchers in the fields of organic chemistry and biochemistry. Its unique structure allows for the efficient formation of peptide bonds while maintaining the integrity of the serine side chain, which is crucial for the synthesis of complex peptides and proteins.

The N-hydroxysuccinimide ester functionality enhances the reactivity of the compound, enabling it to readily react with amines to form stable amide bonds. This property is particularly beneficial in the development of peptide-based therapeutics and in the modification of biomolecules for drug delivery systems. Researchers appreciate its ease of use and the high purity it offers, which contributes to successful outcomes in various applications, including vaccine development and targeted drug delivery.

Synonyms
Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester
CAS Number
158000-21-6
Purity
≥ 98% (HPLC)
Molecular Formula
C26H28N2O7
Molecular Weight
480.4
MDL Number
MFCD00153363
PubChem ID
72812843
Melting Point
96-102 °C
Appearance
White powder
Optical Rotation
[α]D20 = -13 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester
CAS Number
158000-21-6
Purity
≥ 98% (HPLC)
Molecular Formula
C26H28N2O7
Molecular Weight
480.4
MDL Number
MFCD00153363
PubChem ID
72812843
Melting Point
96-102 °C
Appearance
White powder
Optical Rotation
[α]D20 = -13 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-serine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with high specificity and efficiency.
  • Drug Development: It is used in the development of pharmaceutical compounds, particularly in creating targeted drug delivery systems that enhance therapeutic efficacy.
  • Bioconjugation: The chemical is effective in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Protein Engineering: It aids in modifying proteins to improve their stability and functionality, making it valuable in biotechnology and enzyme engineering.
  • Research in Cancer Therapy: This compound is explored in cancer research for its potential to improve the delivery of chemotherapeutic agents directly to tumor cells, enhancing treatment outcomes.

Citations