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Catalog Number:
03735
CAS Number:
109434-27-7
Fmoc-O-tert-butyl-L-serine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester
Purity:
≥ 98% (TLC)
Synonym(s):
Fmoc-L-Ser(tBu)-ODhbt
Documents
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Product Information

Fmoc-O-tert-butyl-L-serine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound features a unique structure that combines the protective Fmoc group with a tert-butyl ester, enhancing its stability and solubility in various organic solvents. Researchers appreciate its role in facilitating the synthesis of complex peptides, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group allows for easy deprotection and subsequent coupling reactions.

Additionally, the incorporation of the benzotriazine moiety provides potential applications in medicinal chemistry, particularly in the development of novel therapeutics. Its unique properties make it an excellent candidate for use in the design of bioactive compounds, offering researchers a reliable tool for exploring new drug candidates. With its favorable characteristics, Fmoc-O-tert-butyl-L-serine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester stands out as a valuable asset in both academic and industrial research settings.

Synonyms
Fmoc-L-Ser(tBu)-ODhbt
CAS Number
109434-27-7
Purity
≥ 98% (TLC)
Molecular Formula
C29H28N4O6
Molecular Weight
528.6
MDL Number
MFCD00133600
PubChem ID
3397129
Appearance
Off-white powder
Optical Rotation
[a]D24 = - 32 ± 2 ° (C=1, in THF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Ser(tBu)-ODhbt
CAS Number
109434-27-7
Purity
≥ 98% (TLC)
Molecular Formula
C29H28N4O6
Molecular Weight
528.6
MDL Number
MFCD00133600
PubChem ID
3397129
Appearance
Off-white powder
Optical Rotation
[a]D24 = - 32 ± 2 ° (C=1, in THF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-serine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions and enhancing the overall yield and purity of the final product.
  • Drug Development: Its unique structure makes it valuable in the design of novel pharmaceuticals, particularly in targeting specific biological pathways, which can lead to more effective treatments.
  • Bioconjugation: It is used in bioconjugation processes to attach biomolecules to drugs or imaging agents, improving their stability and bioavailability in therapeutic applications.
  • Research in Biochemistry: This compound aids in studying protein interactions and functions, providing insights that are crucial for understanding cellular processes and disease mechanisms.
  • Material Science: Its properties can be exploited in the development of new materials, such as polymers, that have specific functionalities for applications in electronics and coatings.

Citations