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Catalog Number:
03733
CAS Number:
111524-95-9
Fmoc-D-phenylglycine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Phg-OH, (R)-Fmoc-2-aminophenylacetic acid
Documents
$25.00 /1G
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Product Information

Fmoc-D-phenylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for easy incorporation into various peptide sequences, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Fmoc-D-phenylglycine is particularly valued for its ability to enhance the stability and bioactivity of peptides, leading to improved therapeutic efficacy in pharmaceutical applications.

In addition to its role in peptide synthesis, Fmoc-D-phenylglycine is also employed in the development of novel therapeutic agents and in the study of protein interactions. Its compatibility with solid-phase peptide synthesis (SPPS) techniques allows for streamlined workflows, enabling researchers to produce complex peptides efficiently. The compound's favorable properties, including its solubility and stability, make it an ideal choice for both academic and industrial applications, ensuring that it meets the rigorous demands of modern research.

Synonyms
Fmoc-D-Phg-OH, (R)-Fmoc-2-aminophenylacetic acid
CAS Number
111524-95-9
Purity
≥ 99% (HPLC)
Molecular Formula
C23H19NO4
Molecular Weight
373.4
MDL Number
MFCD00190891
PubChem ID
3702842
Melting Point
168 - 182 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -81 ± 3 º (C=1% in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Phg-OH, (R)-Fmoc-2-aminophenylacetic acid
CAS Number
111524-95-9
Purity
≥ 99% (HPLC)
Molecular Formula
C23H19NO4
Molecular Weight
373.4
MDL Number
MFCD00190891
PubChem ID
3702842
Melting Point
168 - 182 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -81 ± 3 º (C=1% in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-phenylglycine is widely utilized in research focused on

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures efficiently.
  • Drug Development: It plays a significant role in medicinal chemistry, where it is used to design and develop new pharmaceutical compounds, particularly those targeting specific biological pathways.
  • Bioconjugation: Fmoc-D-phenylglycine can be employed in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: This compound is used in studies related to neurotransmitter systems, helping researchers understand the role of peptides in neural signaling and potential therapeutic applications.
  • Protein Engineering: It is valuable in the field of protein engineering, where it aids in the modification of proteins to enhance their stability and activity, offering advantages over other amino acid derivatives.

Citations