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Catalog Number:
03732
CAS Number:
102410-65-1
Fmoc-L-phenylglycine
Purity:
≥ 99% (Assay)
Synonym(s):
Fmoc-L-Phg-OH, (S-Fmoc-2-aminophenylacetic acid
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Product Information

Fmoc-L-phenylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and reactivity, making it an ideal choice for solid-phase peptide synthesis. Researchers appreciate its ability to facilitate the introduction of phenylglycine residues into peptides, thereby improving the pharmacological properties of the resulting compounds. Its unique structure allows for easy cleavage of the Fmoc group under mild conditions, ensuring that the integrity of sensitive functional groups is maintained during synthesis.

In addition to its applications in peptide synthesis, Fmoc-L-phenylglycine is also valuable in the development of pharmaceuticals and biologically active compounds. Its incorporation into peptide sequences can lead to enhanced binding affinities and improved biological activity, making it a crucial component in the design of therapeutic agents. With its favorable properties and practical applications, Fmoc-L-phenylglycine stands out as a key building block for researchers and industry professionals focused on advancing drug discovery and development.

Synonyms
Fmoc-L-Phg-OH, (S-Fmoc-2-aminophenylacetic acid
CAS Number
102410-65-1
Purity
≥ 99% (Assay)
Molecular Formula
C23H19NO4
Molecular Weight
373.4
MDL Number
MFCD00155632
PubChem ID
3702842
Melting Point
169-182 °C
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Phg-OH, (S-Fmoc-2-aminophenylacetic acid
CAS Number
102410-65-1
Purity
≥ 99% (Assay)
Molecular Formula
C23H19NO4
Molecular Weight
373.4
MDL Number
MFCD00155632
PubChem ID
3702842
Melting Point
169-182 °C
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-phenylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective group allows for selective reactions, enhancing the efficiency of creating complex peptides.
  • Drug Development: In pharmaceutical research, it is used to develop new drugs by modifying peptide structures, which can lead to improved therapeutic properties and reduced side effects.
  • Bioconjugation: Fmoc-L-phenylglycine is employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Protein Engineering: Researchers utilize this compound in the design of novel proteins with specific functionalities, aiding in the creation of enzymes or antibodies with enhanced performance.
  • Research in Neuroscience: It is also explored in neuroscience studies, particularly in the synthesis of neuropeptides, which can help in understanding brain functions and developing treatments for neurological disorders.

Citations