Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
03726
CAS Number:
112883-41-7
Fmoc-D-norleucine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Nle-OH, Fmoc-D-2-aminohexanoic acid
Documents
$30.00 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-D-norleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, characterized by its fluorenylmethoxycarbonyl (Fmoc) protecting group, offers enhanced stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Researchers appreciate its ability to facilitate the formation of complex peptides while maintaining high purity and yield. Fmoc-D-norleucine is particularly valuable in the pharmaceutical industry for developing therapeutic peptides, including those targeting cancer and metabolic disorders. Its unique properties allow for selective deprotection under mild conditions, ensuring that sensitive functional groups remain intact during synthesis.

In addition to its applications in peptide synthesis, Fmoc-D-norleucine serves as a building block in the design of novel biomaterials and drug delivery systems. Its structural features enable the creation of peptides with specific biological activities, paving the way for innovative treatments. With its proven track record in research and industry, Fmoc-D-norleucine stands out as a crucial component for professionals aiming to advance their work in biochemistry and medicinal chemistry.

Synonyms
Fmoc-D-Nle-OH, Fmoc-D-2-aminohexanoic acid
CAS Number
112883-41-7
Purity
≥ 98% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.42
MDL Number
MFCD00155639
PubChem ID
4292404
Melting Point
140 - 146 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 19 ± 3 º (C=1 in DMF) [a]D20 = 6 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Nle-OH, Fmoc-D-2-aminohexanoic acid
CAS Number
112883-41-7
Purity
≥ 98% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.42
MDL Number
MFCD00155639
PubChem ID
4292404
Melting Point
140 - 146 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 19 ± 3 º (C=1 in DMF) [a]D20 = 6 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-norleucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create custom sequences for various applications in drug development and biotechnology.
  • Drug Development: Its unique structure enhances the stability and solubility of peptide drugs, making it valuable in the pharmaceutical industry for developing more effective therapeutic agents.
  • Bioconjugation: Fmoc-D-norleucine can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and targeted drug delivery.
  • Research in Protein Engineering: This compound aids in the design of modified proteins with improved properties, helping researchers explore new functionalities and applications in various fields, including enzyme engineering.
  • Academic Research: It is frequently employed in academic laboratories for studies related to peptide chemistry, providing students and researchers with a practical tool to understand complex biochemical processes.

Citations