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Catalog Number:
03725
CAS Number:
163437-14-7
Fmoc-L-methionine sulfone
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Met(O2)-OH
Documents
$51.18 /1G
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Product Information

Fmoc-L-methionine sulfone is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its sulfone group enhances the stability and solubility of the compound, making it an excellent choice for researchers looking to develop high-purity peptides. Fmoc-L-methionine sulfone is particularly valuable in the pharmaceutical industry for the synthesis of bioactive peptides, where precise control over amino acid sequences is crucial for therapeutic efficacy.

In addition to its applications in peptide synthesis, Fmoc-L-methionine sulfone can also serve as a building block in the development of novel compounds with potential applications in drug discovery and development. Its unique properties allow for improved reaction conditions and yields compared to traditional amino acids, making it a preferred choice for researchers aiming to streamline their synthesis processes. With its robust performance and reliability, Fmoc-L-methionine sulfone stands out as a key reagent in modern chemical research.

Synonyms
Fmoc-L-Met(O2)-OH
CAS Number
163437-14-7
Purity
≥ 98% (HPLC)
Molecular Formula
C20H21NO6S
Molecular Weight
403.5
MDL Number
MFCD00153361
PubChem ID
22490610
Melting Point
151-171 °C
Appearance
White powder
Optical Rotation
[a]D20 = -14 ± 2º (C=1% in DMF)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Met(O2)-OH
CAS Number
163437-14-7
Purity
≥ 98% (HPLC)
Molecular Formula
C20H21NO6S
Molecular Weight
403.5
MDL Number
MFCD00153361
PubChem ID
22490610
Melting Point
151-171 °C
Appearance
White powder
Optical Rotation
[a]D20 = -14 ± 2º (C=1% in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-methionine sulfone is widely utilized in research focused on:

  • Peptide Synthesis: This compound is commonly used as a building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It plays a role in the design of novel therapeutics, particularly in the development of peptide-based drugs that target specific biological pathways.
  • Bioconjugation: The sulfone group provides unique reactivity, making it valuable for attaching peptides to other biomolecules, enhancing drug delivery systems.
  • Research in Protein Engineering: Its application in modifying amino acids helps in studying protein structure and function, aiding in the development of proteins with improved properties.
  • Analytical Chemistry: This compound is used in various analytical techniques, such as mass spectrometry, to identify and quantify peptides, facilitating research in proteomics.

Citations