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Catalog Number:
03713
CAS Number:
111061-55-3
Fmoc-O-trityl-L-homoserine
Purity:
≥ 99.8% (Chiral HPLC)
Synonym(s):
Fmoc-L-HomoSer(Trt)-OH
Documents
$72.31 /1G
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Product Information

Fmoc-O-trityl-L-homoserine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its trityl group enhances stability and solubility, making it an ideal choice for researchers focused on synthesizing high-purity peptides. The unique structure of Fmoc-O-trityl-L-homoserine allows for efficient coupling reactions, facilitating the creation of diverse peptide libraries that are crucial in pharmaceutical research and development.

In addition to its role in peptide synthesis, Fmoc-O-trityl-L-homoserine is also valuable in the study of protein interactions and the development of therapeutic agents. Its ability to serve as a building block for more complex molecules opens avenues for innovative drug design, particularly in targeting specific biological pathways. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis, making it a preferred choice for advancing peptide chemistry and biochemistry applications.

Synonyms
Fmoc-L-HomoSer(Trt)-OH
CAS Number
111061-55-3
Purity
≥ 99.8% (Chiral HPLC)
Molecular Formula
C38H33NO5
Molecular Weight
583.68
MDL Number
MFCD00270544
PubChem ID
13943581
Melting Point
60 - 72 ?C
Appearance
White to off-white crystals
Optical Rotation
[a]20D = -14 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-HomoSer(Trt)-OH
CAS Number
111061-55-3
Purity
≥ 99.8% (Chiral HPLC)
Molecular Formula
C38H33NO5
Molecular Weight
583.68
MDL Number
MFCD00270544
PubChem ID
13943581
Melting Point
60 - 72 ?C
Appearance
White to off-white crystals
Optical Rotation
[a]20D = -14 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-trityl-L-homoserine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it plays a crucial role in the development of new drugs by facilitating the creation of complex peptide structures that can lead to innovative therapeutic agents.
  • Bioconjugation: It is used in bioconjugation processes, linking biomolecules like proteins and antibodies to enhance their functionality, which is vital in creating targeted therapies and diagnostics.
  • Research in Neuroscience: The compound is applied in studies related to neurotransmitter systems, helping researchers understand the role of homoserine in brain function and potential implications in neurodegenerative diseases.
  • Custom Synthesis Services: Many contract research organizations utilize this compound for custom synthesis projects, offering tailored solutions for clients in academia and industry looking to develop specific compounds efficiently.

Citations