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Catalog Number:
03712
CAS Number:
210755-31-0
Nα-Fmoc-Nim-Boc-D-histidine cyclohexylammonium salt
Purity:
≥ 99% (TLC)
Synonym(s):
Fmoc-D-His(Boc)-OH×CHA
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Product Information

Na-Fmoc-Nim-Boc-D-histidine cyclohexylammonium salt is a versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which facilitates the solid-phase synthesis of peptides by providing a stable protecting group that can be easily removed under mild conditions. Its unique structure enhances the stability and solubility of peptides, making it an ideal choice for researchers focused on developing therapeutic peptides and proteins.

This compound is particularly beneficial in the pharmaceutical industry, where it is employed in the design of peptide-based drugs, including those targeting cancer and metabolic disorders. The cyclohexylammonium salt form enhances its solubility in organic solvents, allowing for more efficient reactions and purification processes. Researchers appreciate its ability to streamline synthesis while maintaining high yields and purity, making Na-Fmoc-Nim-Boc-D-histidine cyclohexylammonium salt a valuable tool in modern biochemistry and medicinal chemistry.

Synonyms
Fmoc-D-His(Boc)-OH×CHA
CAS Number
210755-31-0
Purity
≥ 99% (TLC)
Molecular Formula
C26H27N3O6×C6H13N
Molecular Weight
576.7
MDL Number
MFCD00270617
PubChem ID
91976892
Melting Point
153 - 155 ?C
Optical Rotation
[a]20D = -10 ± 1 º (C=1 in Methanol)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-His(Boc)-OH×CHA
CAS Number
210755-31-0
Purity
≥ 99% (TLC)
Molecular Formula
C26H27N3O6×C6H13N
Molecular Weight
576.7
MDL Number
MFCD00270617
PubChem ID
91976892
Melting Point
153 - 155 ?C
Optical Rotation
[a]20D = -10 ± 1 º (C=1 in Methanol)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nim-Boc-D-histidine cyclohexylammonium salt is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development and biochemistry.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new therapeutics, particularly in targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, enhancing their efficacy and specificity.
  • Protein Engineering: Researchers utilize this chemical to modify proteins, improving their stability and activity, which is crucial in developing enzyme-based therapies.
  • Research in Cancer Therapy: The compound's ability to interact with specific receptors makes it a candidate for research in targeted cancer therapies, potentially leading to more effective treatment options.

Citations