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Catalog Number:
03672
CAS Number:
3392-09-4
Boc-L-leucine N-hydoxysuccinimide ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Leu-OSu
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Product Information

Boc-L-leucine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound serves as a valuable building block for the formation of peptide bonds, facilitating the efficient coupling of amino acids in the development of peptides and proteins. Its unique structure, featuring a Boc (tert-butyloxycarbonyl) protecting group, allows for selective deprotection under mild conditions, making it particularly advantageous for sensitive biological applications. Researchers in the fields of medicinal chemistry and drug development can leverage this compound to create targeted therapeutics and biologically active peptides, enhancing the specificity and efficacy of their formulations.

In addition to its role in peptide synthesis, Boc-L-leucine N-hydroxysuccinimide ester is also employed in the preparation of various bioconjugates, including antibody-drug conjugates (ADCs) and other targeted delivery systems. Its ability to form stable linkages with biomolecules opens up new avenues for the development of innovative therapeutic strategies. With its favorable properties and practical applications, this compound stands out as a key reagent for researchers and industry professionals aiming to advance their work in peptide chemistry and bioconjugation.

Synonyms
Boc-L-Leu-OSu
CAS Number
3392-09-4
Purity
≥ 99% (HPLC)
Molecular Formula
C15H24N2O6
Molecular Weight
328.37
MDL Number
MFCD00037913
PubChem ID
100124
Melting Point
112 - 118 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -43 ± 2 º (C=1 in dioxane)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Leu-OSu
CAS Number
3392-09-4
Purity
≥ 99% (HPLC)
Molecular Formula
C15H24N2O6
Molecular Weight
328.37
MDL Number
MFCD00037913
PubChem ID
100124
Melting Point
112 - 118 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -43 ± 2 º (C=1 in dioxane)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-leucine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing for the introduction of leucine residues, which are crucial for protein structure and function.
  • Drug Development: It is used in the design of prodrugs that enhance the solubility and bioavailability of therapeutic agents, improving their effectiveness in clinical applications.
  • Bioconjugation: The ester functionality enables efficient conjugation with biomolecules, facilitating the development of targeted drug delivery systems and diagnostic agents.
  • Research in Biochemistry: Researchers utilize this compound to study protein interactions and modifications, providing insights into various biological processes and disease mechanisms.
  • Custom Synthesis Services: It is often employed by chemical manufacturers and laboratories for custom synthesis projects, catering to specific research needs and applications in various industries.

Citations