Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
03530
CAS Number:
98929-98-7
Nα,im-Bis-Fmoc-L-histidine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-His(Fmoc)-OH
Documents
$30.20 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Na,im-Bis-Fmoc-L-histidine is a highly versatile amino acid derivative, primarily utilized in peptide synthesis and bioconjugation applications. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective deprotection of amino acids during solid-phase peptide synthesis. Its structure allows for enhanced stability and solubility, making it an excellent choice for researchers focused on developing complex peptides and proteins.

In the pharmaceutical and biotechnology industries, Na,im-Bis-Fmoc-L-histidine is particularly valuable for the synthesis of histidine-containing peptides, which are crucial for various biological functions and therapeutic applications. Its ability to form stable complexes with metal ions also opens avenues for research in catalysis and drug delivery systems. Researchers appreciate its high purity and reliability, ensuring consistent results in experimental setups. With its robust performance in peptide synthesis, this compound stands out as a preferred choice for professionals seeking efficiency and precision in their work.

Synonyms
Fmoc-L-His(Fmoc)-OH
CAS Number
98929-98-7
Purity
≥ 98% (HPLC)
Molecular Formula
C36H29N3O6
Molecular Weight
599.6
MDL Number
MFCD00070658
PubChem ID
74764879
Melting Point
135 - 155 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -5 ± 2 ° (C=4 in DMF) [a]D20 = 9 ± 0.5 º (C=0.5 in Dioxane)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-His(Fmoc)-OH
CAS Number
98929-98-7
Purity
≥ 98% (HPLC)
Molecular Formula
C36H29N3O6
Molecular Weight
599.6
MDL Number
MFCD00070658
PubChem ID
74764879
Melting Point
135 - 155 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -5 ± 2 ° (C=4 in DMF) [a]D20 = 9 ± 0.5 º (C=0.5 in Dioxane)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na,im-Bis-Fmoc-L-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex biomolecules with high purity and yield.
  • Drug Development: It plays a significant role in pharmaceutical research, especially in the design of histidine-containing peptides that can enhance drug solubility and stability, making them more effective in therapeutic applications.
  • Bioconjugation: This chemical is used in bioconjugation processes to attach drugs or imaging agents to proteins, enhancing their functionality and targeting capabilities in medical diagnostics and treatments.
  • Research in Enzyme Activity: It is utilized in studies investigating enzyme mechanisms and interactions, particularly those involving histidine residues, providing insights into metabolic pathways and potential drug targets.
  • Protein Engineering: The compound is valuable in protein engineering, where it aids in the design of novel proteins with specific properties, contributing to advancements in biotechnology and synthetic biology.

Citations