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Catalog Number:
03448
CAS Number:
143688-83-9
Fmoc-D-isoleucine
Purity:
≥ 99% (Assay)
Synonym(s):
Fmoc-D-Ile-OH, Fmoc-(2R,3R)-2-amino-3-methylpentanoic acid
Documents
$150.90 /250MG
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Product Information

Fmoc-D-isoleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it a preferred choice for researchers in the fields of biochemistry and medicinal chemistry. Fmoc-D-isoleucine is particularly valuable in the synthesis of cyclic peptides and complex biomolecules, where precision and purity are paramount.

In addition to its role in peptide synthesis, Fmoc-D-isoleucine has applications in the development of pharmaceuticals and therapeutic agents. Its ability to enhance the stability and bioavailability of peptides makes it an attractive option for drug formulation. Researchers appreciate its compatibility with various coupling reagents and its ease of removal under mild conditions, ensuring that the integrity of the final product is maintained. This compound stands out for its reliability and effectiveness, making it an essential tool for professionals engaged in peptide chemistry and drug discovery.

Synonyms
Fmoc-D-Ile-OH, Fmoc-(2R,3R)-2-amino-3-methylpentanoic acid
CAS Number
143688-83-9
Purity
≥ 99% (Assay)
Molecular Formula
C21H23NO4
Molecular Weight
353.4
MDL Number
MFCD00080291
PubChem ID
100103
Melting Point
146 - 150 ºC (Lit.)
Appearance
White powder
Optical Rotation
[a]D25 = 10 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Ile-OH, Fmoc-(2R,3R)-2-amino-3-methylpentanoic acid
CAS Number
143688-83-9
Purity
≥ 99% (Assay)
Molecular Formula
C21H23NO4
Molecular Weight
353.4
MDL Number
MFCD00080291
PubChem ID
100103
Melting Point
146 - 150 ºC (Lit.)
Appearance
White powder
Optical Rotation
[a]D25 = 10 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-isoleucine is widely utilized in research focused on:

  • Peptide Synthesis: It serves as a key building block in solid-phase peptide synthesis, allowing chemists to create complex peptides efficiently.
  • Drug Development: This compound is important in the pharmaceutical industry for developing peptide-based drugs, enhancing bioactivity and stability.
  • Biotechnology: Used in the production of peptide therapeutics, it aids in creating targeted treatments for various diseases, including cancer and diabetes.
  • Research Applications: It is utilized in academic and industrial research for studying protein interactions and functions, contributing to advancements in molecular biology.
  • Custom Peptide Libraries: Fmoc-D-isoleucine is essential for generating diverse peptide libraries, facilitating high-throughput screening for drug discovery.

Citations