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Catalog Number:
03316
CAS Number:
5854-78-4
O-tert-Butyl-L-threonine-tert-butyl ester
Purity:
≥ 99% (GC)
Synonym(s):
L-Thr(tBu)-OtBu
Documents
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Product Information

O-tert-Butyl-L-threonine-tert-butyl ester is a versatile compound widely recognized for its applications in peptide synthesis and pharmaceutical research. This amino acid derivative, characterized by its stable tert-butyl ester group, enhances solubility and reactivity, making it an ideal choice for researchers looking to develop novel therapeutic agents. Its unique structure allows for efficient incorporation into peptides, facilitating the study of protein interactions and enzyme activity.

In the realm of medicinal chemistry, O-tert-Butyl-L-threonine-tert-butyl ester serves as a valuable building block for the synthesis of bioactive compounds, particularly in the development of inhibitors and modulators. Its favorable properties, including high stability and ease of handling, make it a preferred choice for both academic and industrial applications. Researchers can leverage this compound to streamline their synthesis processes and improve yields, ultimately accelerating the development of new drugs and therapeutic strategies.

Synonyms
L-Thr(tBu)-OtBu
CAS Number
5854-78-4
Purity
≥ 99% (GC)
Molecular Formula
C12H25NO3
Molecular Weight
231.34
MDL Number
MFCD00077109
PubChem ID
5171899
Appearance
Light yellowish liquid
Optical Rotation
[a]20D = + 12 ± 2º (C=2 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
L-Thr(tBu)-OtBu
CAS Number
5854-78-4
Purity
≥ 99% (GC)
Molecular Formula
C12H25NO3
Molecular Weight
231.34
MDL Number
MFCD00077109
PubChem ID
5171899
Appearance
Light yellowish liquid
Optical Rotation
[a]20D = + 12 ± 2º (C=2 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

O-tert-Butyl-L-threonine-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, enhancing the stability and solubility of the resulting products, which is crucial for pharmaceutical applications.
  • Drug Development: It plays a significant role in the development of new therapeutic agents, particularly in creating prodrugs that improve bioavailability and reduce side effects.
  • Biochemical Research: Researchers use this compound to study enzyme activity and protein interactions, providing insights into metabolic pathways and disease mechanisms.
  • Cosmetic Formulations: Its properties allow for incorporation into skincare products, promoting better absorption of active ingredients and enhancing product efficacy.
  • Food Industry Applications: The compound can be utilized in food science for the development of flavor enhancers or preservatives, contributing to improved food quality and shelf life.

Citations