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Catalog Number:
03279
CAS Number:
61043-41-2
Ala-Ala-Phe-pNA
Purity:
≥ 99% (Assay)
Synonym(s):
Ala-Ala-Phe p-nitroanilide
Documents
$72.31 /50MG
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Product Information

Ala-Ala-Phe-pNA is a synthetic peptide that serves as a valuable substrate in biochemical research, particularly in the study of proteolytic enzymes. This compound is recognized for its ability to mimic natural peptide bonds, making it an ideal choice for enzyme assays and screening applications. Researchers utilize Ala-Ala-Phe-pNA to investigate the activity of various proteases, which play crucial roles in numerous biological processes, including digestion, immune response, and cell signaling. The incorporation of a p-nitroanilide moiety allows for easy spectrophotometric detection, enhancing its utility in laboratory settings.

In addition to its applications in enzyme kinetics, Ala-Ala-Phe-pNA can also be employed in drug development and therapeutic research, where understanding protease activity is essential for designing effective inhibitors. Its specificity and sensitivity make it a preferred choice for researchers aiming to explore the intricacies of proteolytic pathways. With its robust performance in various assays, Ala-Ala-Phe-pNA stands out as a reliable tool for advancing biochemical knowledge and therapeutic innovations.

Synonyms
Ala-Ala-Phe p-nitroanilide
CAS Number
61043-41-2
Purity
≥ 99% (Assay)
Molecular Formula
C21H25N5O5
Molecular Weight
427.46
MDL Number
MFCD00057666
PubChem ID
4304044
Melting Point
201 - 207 ?C
Appearance
White powder
Optical Rotation
[a]D20 = + 32 ± 2º (C=0.5 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Ala-Ala-Phe p-nitroanilide
CAS Number
61043-41-2
Purity
≥ 99% (Assay)
Molecular Formula
C21H25N5O5
Molecular Weight
427.46
MDL Number
MFCD00057666
PubChem ID
4304044
Melting Point
201 - 207 ?C
Appearance
White powder
Optical Rotation
[a]D20 = + 32 ± 2º (C=0.5 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ala-Ala-Phe-pNA is widely utilized in research focused on:

  • Biochemical Assays: This compound serves as a substrate in enzyme assays, particularly for proteases. Its specificity allows researchers to measure enzyme activity accurately, facilitating drug discovery and development.
  • Peptide Synthesis: Used in the synthesis of peptides, Ala-Ala-Phe-pNA helps in studying peptide interactions and stability, which is crucial for developing new therapeutic agents.
  • Drug Development: The compound is instrumental in screening potential drug candidates by evaluating their interactions with specific enzymes, aiding pharmaceutical companies in identifying effective treatments.
  • Diagnostic Tools: It can be incorporated into diagnostic assays to detect enzyme-related diseases, providing healthcare professionals with essential tools for early diagnosis and treatment planning.
  • Research on Protein Folding: This chemical aids in understanding protein folding mechanisms, which is vital for comprehending various diseases linked to misfolded proteins, thus contributing to advancements in medical research.

Citations