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Catalog Number:
03218
CAS Number:
148625-77-8
Fmoc-L-prolinol
Purity:
≥ 99% (Assay)
Synonym(s):
(S-Boc-2-pyrrolidinemethanol
Documents
$36.65 /1G
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Product Information

Fmoc-L-prolinol is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound, recognized for its unique structure, features a fluorenylmethoxycarbonyl (Fmoc) protecting group that enhances its stability and reactivity. Researchers appreciate Fmoc-L-prolinol for its ability to facilitate the formation of peptide bonds, making it an essential component in the development of peptide-based therapeutics and drug candidates. Its application extends to the synthesis of complex natural products and the creation of novel biomolecules, showcasing its significance in advancing pharmaceutical research.

In addition to its role in peptide synthesis, Fmoc-L-prolinol is also valued for its potential in asymmetric synthesis and catalysis, where it can serve as a chiral auxiliary. This characteristic allows for the production of enantiomerically pure compounds, which are crucial in the development of effective pharmaceuticals. With its robust performance and adaptability, Fmoc-L-prolinol stands out as a key reagent for researchers and industry professionals aiming to innovate in drug discovery and development.

Synonyms
(S-Boc-2-pyrrolidinemethanol
CAS Number
148625-77-8
Purity
≥ 99% (Assay)
Molecular Formula
C20H21NO3
Molecular Weight
323.4
MDL Number
MFCD00235942
PubChem ID
4234884
Appearance
White or off-white Powder
Optical Rotation
[a]D20 = -42 to -38º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
(S-Boc-2-pyrrolidinemethanol
CAS Number
148625-77-8
Purity
≥ 99% (Assay)
Molecular Formula
C20H21NO3
Molecular Weight
323.4
MDL Number
MFCD00235942
PubChem ID
4234884
Appearance
White or off-white Powder
Optical Rotation
[a]D20 = -42 to -38º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-prolinol is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, which are crucial in drug development and biological research. Its Fmoc protecting group allows for easy removal during the synthesis process, enhancing efficiency.
  • Drug Development: Researchers leverage Fmoc-L-prolinol to create novel pharmaceutical compounds. Its unique structure can lead to the development of drugs with improved efficacy and reduced side effects.
  • Bioconjugation: The compound is utilized in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating the creation of targeted drug delivery systems.
  • Material Science: In the field of material science, Fmoc-L-prolinol is used to develop smart materials that respond to environmental stimuli, making it valuable in creating advanced coatings and sensors.
  • Research in Neuroscience: This compound is also explored in neuroscience research for its potential role in modulating neurotransmitter systems, which could lead to breakthroughs in understanding neurological disorders.

Citations