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Catalog Number:
03127
CAS Number:
15028-39-4
L-Phenylglycine methyl ester hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
L-Phg-OMe·HCl, (S-(+)-2-Aminophenylacetic acid methyl esterhydrochloride
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Product Information

L-Phenylglycine methyl ester hydrochloride is a versatile compound widely utilized in the synthesis of pharmaceuticals and agrochemicals. This hydrochloride salt of L-Phenylglycine methyl ester exhibits excellent solubility, making it an ideal intermediate in the production of various bioactive molecules. Its unique structure allows for the incorporation of phenyl groups, which can enhance the biological activity of the resulting compounds. Researchers often leverage this compound in the development of chiral catalysts and as a building block in the synthesis of amino acid derivatives, which are crucial in medicinal chemistry and drug formulation.

In addition to its applications in pharmaceutical synthesis, L-Phenylglycine methyl ester hydrochloride is also valuable in the field of organic chemistry for its role in asymmetric synthesis. Its ability to facilitate the formation of chiral centers makes it a preferred choice for chemists aiming to create enantiomerically pure compounds. The compound's stability and ease of handling further contribute to its appeal in laboratory settings, ensuring that it meets the rigorous demands of both research and industrial applications.

Synonyms
L-Phg-OMe·HCl, (S-(+)-2-Aminophenylacetic acid methyl esterhydrochloride
CAS Number
15028-39-4
Purity
≥ 99% (HPLC)
Molecular Formula
C9H11NO2·HCl
Molecular Weight
201.7
MDL Number
MFCD00077158
PubChem ID
2827638
Melting Point
187-189 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +142.8 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
L-Phg-OMe·HCl, (S-(+)-2-Aminophenylacetic acid methyl esterhydrochloride
CAS Number
15028-39-4
Purity
≥ 99% (HPLC)
Molecular Formula
C9H11NO2·HCl
Molecular Weight
201.7
MDL Number
MFCD00077158
PubChem ID
2827638
Melting Point
187-189 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +142.8 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

L-Phenylglycine methyl ester hydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in creating amino acid derivatives that can enhance drug efficacy.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific biological activities, which are crucial in drug discovery.
  • Chiral Catalysis: The compound acts as a chiral auxiliary in asymmetric synthesis, helping chemists produce enantiomerically pure compounds, which are essential in the development of safe and effective medications.
  • Biochemical Research: It is utilized in studies involving neurotransmitter systems, aiding in the understanding of various neurological conditions and the development of potential treatments.
  • Material Science: The compound can be incorporated into polymer matrices to enhance material properties, making it valuable in the production of advanced materials for various industrial applications.

Citations