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Catalog Number:
03077
CAS Number:
383-70-0
Trifluoroacetyl glycine
Purity:
≥ 99% (HPLC)
Synonym(s):
TFA-Gly-OH, N-(Trifluoroacetyl)aminoacetic acid
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Product Information

Trifluoroacetyl glycine is a versatile compound known for its unique trifluoromethyl group, which enhances its reactivity and solubility in various solvents. This compound is particularly valuable in the synthesis of pharmaceuticals and agrochemicals, where it serves as an important intermediate. Its ability to modify biological activity makes it a crucial component in drug discovery and development, especially in the design of novel therapeutic agents. Researchers appreciate its role in peptide synthesis and as a building block for fluorinated compounds, which are increasingly relevant in medicinal chemistry due to their improved metabolic stability and bioavailability.

In addition to its applications in pharmaceuticals, trifluoroacetyl glycine is also utilized in the production of specialty chemicals and as a reagent in organic synthesis. Its unique properties allow for selective reactions that can lead to the formation of complex molecular structures, making it an essential tool for chemists in both academic and industrial settings. The compound's stability and ease of handling further enhance its appeal, ensuring that it meets the rigorous demands of modern chemical research and development.

Synonyms
TFA-Gly-OH, N-(Trifluoroacetyl)aminoacetic acid
CAS Number
383-70-0
Purity
≥ 99% (HPLC)
Molecular Formula
C4H4NO3F3
Molecular Weight
171.1
MDL Number
MFCD00029784
PubChem ID
136227
Melting Point
117-121 °C
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
TFA-Gly-OH, N-(Trifluoroacetyl)aminoacetic acid
CAS Number
383-70-0
Purity
≥ 99% (HPLC)
Molecular Formula
C4H4NO3F3
Molecular Weight
171.1
MDL Number
MFCD00029784
PubChem ID
136227
Melting Point
117-121 °C
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Trifluoroacetyl glycine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and analgesic drugs.
  • Biochemical Research: It is used as a reagent in peptide synthesis, aiding researchers in the creation of complex biomolecules for studying protein interactions and functions.
  • Fluorinated Compounds: The unique trifluoroacetyl group enhances the properties of compounds, making them more effective in applications such as drug design and agrochemicals.
  • Analytical Chemistry: Trifluoroacetyl glycine is employed as a derivatizing agent in chromatography, improving the detection and analysis of amino acids and other small molecules.
  • Material Science: It is used in the development of fluorinated polymers, which exhibit superior chemical resistance and thermal stability, beneficial for various industrial applications.

Citations