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Catalog Number:
03025
CAS Number:
66036-77-9
Nω-Nitro-D-arginine
Purity:
≥ 98% (HPLC)
Synonym(s):
D-Arg(NO2)-OH
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Product Information

Nw-Nitro-D-arginine is a potent nitric oxide synthase inhibitor that plays a crucial role in various biochemical and pharmacological applications. This compound is particularly valuable in research settings focused on cardiovascular health, neurobiology, and cancer studies, where modulation of nitric oxide levels is essential. Its unique structure allows for targeted inhibition of nitric oxide production, making it an important tool for scientists investigating the role of nitric oxide in physiological and pathological processes.

In practical applications, Nw-Nitro-D-arginine has been utilized in studies examining the effects of nitric oxide on blood pressure regulation and vascular function. Additionally, it serves as a critical reagent in the development of therapeutic strategies aimed at diseases characterized by excessive nitric oxide production, such as sepsis and certain types of cancer. Researchers appreciate its specificity and effectiveness, which can lead to more precise experimental outcomes compared to other nitric oxide synthase inhibitors.

Synonyms
D-Arg(NO2)-OH
CAS Number
66036-77-9
Purity
≥ 98% (HPLC)
Molecular Formula
C6H13N5O4
Molecular Weight
219.2
MDL Number
MFCD00066013
PubChem ID
4367
Melting Point
236-247 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -22.0 ± 2º (C=2% in 2N HCl)
Conditions
Store at RT
General Information
Synonyms
D-Arg(NO2)-OH
CAS Number
66036-77-9
Purity
≥ 98% (HPLC)
Molecular Formula
C6H13N5O4
Molecular Weight
219.2
MDL Number
MFCD00066013
PubChem ID
4367
Melting Point
236-247 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -22.0 ± 2º (C=2% in 2N HCl)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nw-Nitro-D-arginine is widely utilized in research focused on:

  • Cardiovascular Research: This compound is often used to study nitric oxide synthesis and its role in regulating blood pressure, helping researchers understand cardiovascular diseases.
  • Neurobiology: It serves as a tool to investigate the effects of nitric oxide in the nervous system, aiding in the development of treatments for neurodegenerative disorders.
  • Pharmacology: Nw-Nitro-D-arginine is employed in drug development to assess the impact of nitric oxide modulation on various therapeutic agents, enhancing drug efficacy.
  • Immunology: Researchers utilize this compound to explore its effects on immune responses, potentially leading to advancements in treatments for autoimmune diseases.
  • Biochemical Studies: It is used in laboratory experiments to analyze enzyme activities related to nitric oxide production, providing insights into metabolic pathways.

Citations