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Catalog Number:
02901
CAS Number:
135112-28-6
Fmoc-L-norvaline
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Nva-OH, Fmoc-L-2-aminovaleric acid
Documents
$29.34 /1G
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Product Information

Fmoc-L-norvaline is a versatile amino acid derivative widely utilized in peptide synthesis and research applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Its unique structure allows for the incorporation of norvaline into peptides, providing researchers with the ability to study the effects of this non-standard amino acid on protein folding, stability, and function.

In addition to its role in academic research, Fmoc-L-norvaline is increasingly being explored in pharmaceutical development, particularly in the design of novel therapeutics that target specific biological pathways. Its ability to modify peptide properties can lead to improved bioavailability and efficacy of drug candidates. With its favorable characteristics, Fmoc-L-norvaline stands out as a valuable tool for chemists and biochemists aiming to innovate in peptide-based applications.

Synonyms
Fmoc-L-Nva-OH, Fmoc-L-2-aminovaleric acid
CAS Number
135112-28-6
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4
Molecular Weight
339.4
MDL Number
MFCD00155631
PubChem ID
4349990
Appearance
White powder
Optical Rotation
[a]20D = -21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Nva-OH, Fmoc-L-2-aminovaleric acid
CAS Number
135112-28-6
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4
Molecular Weight
339.4
MDL Number
MFCD00155631
PubChem ID
4349990
Appearance
White powder
Optical Rotation
[a]20D = -21 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-norvaline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various reaction conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, Fmoc-L-norvaline is used to create novel peptide-based drugs. Its unique structure can enhance the bioactivity of therapeutic peptides, making it valuable in drug formulation.
  • Biotechnology: This chemical plays a role in the production of recombinant proteins. By incorporating Fmoc-L-norvaline into expression systems, researchers can improve protein yield and functionality.
  • Diagnostics: In the field of diagnostics, it is used in the development of peptide-based assays. These assays can detect specific biomarkers, aiding in disease diagnosis and monitoring.
  • Research on Protein Folding: Fmoc-L-norvaline is utilized in studies investigating protein folding and stability. Understanding these processes is crucial for developing therapies for diseases related to protein misfolding.

Citations