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Catalog Number:
02882
CAS Number:
187618-60-6
Nα-Fmoc-Nω-(2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl)-D-arginine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-Arg(Pbf)-OH
Documents
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Product Information

Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to enhance the solubility and stability of peptides, making it an essential building block for researchers focused on developing therapeutic agents. Its unique structure, featuring a sulfonyl group and a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for selective reactions, facilitating the synthesis of complex peptide sequences with precision.

In addition to its applications in peptide synthesis, this compound is also utilized in the design of targeted drug delivery systems, where its properties can be exploited to improve the pharmacokinetics of bioactive peptides. Researchers in pharmaceutical development can benefit from its ability to modulate biological activity and improve the efficacy of peptide-based drugs. With its robust profile and versatility, Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine stands out as a valuable tool for advancing peptide research and development.

Synonyms
Fmoc-D-Arg(Pbf)-OH
CAS Number
187618-60-6
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C34H40N4O7S
Molecular Weight
648.77
MDL Number
MFCD00237010
PubChem ID
5060264
Appearance
White powder
Optical Rotation
[a]D25 = 4.5 ± 1.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Arg(Pbf)-OH
CAS Number
187618-60-6
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C34H40N4O7S
Molecular Weight
648.77
MDL Number
MFCD00237010
PubChem ID
5060264
Appearance
White powder
Optical Rotation
[a]D25 = 4.5 ± 1.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing researchers to selectively modify amino acids without affecting others, thus streamlining the process.
  • Drug Development: Its unique structure aids in the design of novel therapeutics, particularly in targeting specific biological pathways, making it valuable in pharmaceutical research.
  • Bioconjugation: The sulfonyl group enhances the compound's reactivity, facilitating the attachment of biomolecules, which is crucial in creating targeted drug delivery systems.
  • Analytical Chemistry: Used as a standard in various analytical techniques, it helps in the quantification and characterization of complex mixtures, ensuring accurate results in research.
  • Biomedical Research: Its applications in studying protein interactions and cellular mechanisms provide insights into disease processes, aiding in the development of new diagnostic tools.

Citations