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Catalog Number:
02850
CAS Number:
72086-72-7
Boc-L-glutamic acid α-methyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Glu-OMe
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Product Information

Boc-L-glutamic acid a-methyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of glutamic acid features a Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for various applications in organic chemistry. Its unique structure allows for selective reactions, facilitating the formation of complex peptides and other bioactive molecules. Researchers often employ this compound in the development of drug candidates, particularly in the fields of neuropharmacology and immunology, where glutamic acid derivatives play a crucial role in neurotransmitter function and immune response modulation.

In addition to its applications in peptide synthesis, Boc-L-glutamic acid a-methyl ester serves as a valuable intermediate in the production of amino acid derivatives and other fine chemicals. Its ability to undergo further transformations while maintaining the integrity of the Boc protecting group makes it a preferred choice for chemists seeking efficiency and reliability in their synthetic pathways. With its broad range of applications and favorable properties, this compound stands out as a key ingredient for researchers and industry professionals aiming to innovate in the fields of pharmaceuticals and biochemistry.

Synonyms
Boc-L-Glu-OMe
CAS Number
72086-72-7
Purity
≥ 98% (HPLC)
Molecular Formula
C11H19NO6
Molecular Weight
261.4
MDL Number
MFCD00076931
PubChem ID
13943072
Appearance
White crystalline powder or light yellowish oil
Optical Rotation
[a]D20 = -32.5 ± 2.5º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Boc-L-Glu-OMe
CAS Number
72086-72-7
Purity
≥ 98% (HPLC)
Molecular Formula
C11H19NO6
Molecular Weight
261.4
MDL Number
MFCD00076931
PubChem ID
13943072
Appearance
White crystalline powder or light yellowish oil
Optical Rotation
[a]D20 = -32.5 ± 2.5º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamic acid a-methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for various biological studies.
  • Drug Development: It plays a role in the development of pharmaceuticals, particularly in creating compounds that target specific biological pathways, enhancing drug efficacy.
  • Bioconjugation: The chemical is used in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, facilitating research in diagnostics and therapeutics.
  • Protein Engineering: It is valuable in modifying proteins to improve their stability and functionality, which is crucial in fields like biotechnology and enzyme engineering.
  • Research on Neurotransmitters: The compound aids in studying glutamate receptors, contributing to advancements in understanding neurological disorders and developing potential treatments.

Citations