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Catalog Number:
02781
Nα-Boc-L-tryptophan Merrifield resin (0.25 - 1.0 meq/g, 100 - 200 mesh)
Synonym(s):
Boc-L-Trp-Merrifield resin
Documents
$18.53 /1G
Pack Size Availability Price
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Product Information

Na-Boc-L-tryptophan Merrifield is a protected form of the amino acid L-tryptophan, widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butyloxycarbonyl (Boc) protective group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Researchers appreciate its role in facilitating the assembly of complex peptides, particularly in the development of therapeutic proteins and biologically active compounds. The Boc group can be easily removed under mild acidic conditions, allowing for the seamless integration of L-tryptophan into various peptide sequences.

In addition to its applications in peptide synthesis, Na-Boc-L-tryptophan Merrifield is also valuable in the study of neurotransmitter pathways and the synthesis of tryptophan derivatives, which are crucial in the production of serotonin and melatonin. Its unique properties and versatility make it a preferred choice for researchers aiming to explore the biochemical roles of tryptophan and its derivatives in various biological systems.

Synonyms
Boc-L-Trp-Merrifield resin
MDL Number
MFCD00801290
Substitution
0.25 - 1.0 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Boc-L-Trp-Merrifield resin
MDL Number
MFCD00801290
Substitution
0.25 - 1.0 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-L-tryptophan Merrifield is widely utilized in research focused on

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, enabling researchers to create complex proteins for various studies in biochemistry and molecular biology.
  • Drug Development: Its role in drug design allows for the exploration of new therapeutic agents, particularly in the fields of oncology and neurology, where tryptophan derivatives can influence neurotransmitter pathways.
  • Protein Engineering: By incorporating Na-Boc-L-tryptophan into protein structures, scientists can modify protein functions, enhancing stability and activity for applications in biotechnology.
  • Research in Neuroscience: This compound is used to study the effects of tryptophan on serotonin production, which is crucial for understanding mood disorders and developing antidepressants.
  • Bioconjugation Techniques: It serves as a versatile reagent in bioconjugation, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.

Citations