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Catalog Number:
02779
Boc-O-benzyl-L-threonine Merrifield resin (0.8 - 1.2 meq/g, 100 - 200 mesh)
Synonym(s):
Boc-L-Thr(Bzl)-Merrifield resin
Documents
$18.53 /1G
Pack Size Availability Price
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Product Information

Boc-O-benzyl-L-threonine Merrifield is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound serves as a crucial building block in the development of peptides, particularly in solid-phase peptide synthesis, where its protective Boc (tert-butyloxycarbonyl) group allows for selective reactions while maintaining the integrity of the threonine side chain. Its benzyl group enhances solubility and stability, making it an ideal choice for researchers looking to create complex peptide structures with improved yields and purity.

In addition to its role in peptide synthesis, Boc-O-benzyl-L-threonine Merrifield has applications in the development of biologically active compounds and therapeutic agents. Its unique structure allows for the incorporation of threonine into various peptide sequences, which can be essential for achieving desired biological activities. Researchers in the fields of medicinal chemistry and biochemistry will find this compound particularly beneficial for exploring new drug candidates and optimizing peptide-based therapies.

Synonyms
Boc-L-Thr(Bzl)-Merrifield resin
MDL Number
MFCD00801208
Substitution
0.8 - 1.2 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
General Information
Synonyms
Boc-L-Thr(Bzl)-Merrifield resin
MDL Number
MFCD00801208
Substitution
0.8 - 1.2 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-O-benzyl-L-threonine Merrifield is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Protein Engineering: It is used in the modification of proteins, helping scientists to enhance stability and activity, which is crucial in biopharmaceutical applications.
  • Research in Drug Design: The compound aids in the design of new therapeutic agents by providing a versatile structure that can be tailored for specific biological targets.
  • Bioconjugation: It is employed in bioconjugation processes, linking biomolecules with drugs or imaging agents, thus improving the efficacy and specificity of treatments.
  • Analytical Chemistry: This chemical is also used in analytical methods to study protein interactions and dynamics, contributing to advancements in molecular biology.

Citations