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Catalog Number:
02764
Nα-Boc-Nim-4-toluenesulfonyl-L-histidine Merrifield resin (0.25 - 1.0 meq/g, 100 - 200 mesh)
Synonym(s):
Boc-L-His(Tos)-Merrifield resin
Documents
$18.53 /1G
Pack Size Availability Price
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Product Information

Na-Boc-Nim-4-toluenesulfonyl-L-histidine Merrifield is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity during various chemical reactions. Its unique structure allows for selective coupling in solid-phase peptide synthesis, making it an essential building block for researchers aiming to create complex peptides with high purity and yield. The incorporation of the toluenesulfonyl group further improves the compound's solubility and compatibility with a range of solvents, facilitating its use in diverse laboratory settings.

Researchers and industry professionals benefit from Na-Boc-Nim-4-toluenesulfonyl-L-histidine Merrifield's ability to streamline the synthesis of bioactive peptides, which are crucial in pharmaceuticals and biotechnology. Its application extends to the development of therapeutic agents, where precise peptide sequences are vital for efficacy. With its reliable performance and ease of use, this compound stands out as a preferred choice for those engaged in peptide research and development, offering significant advantages over traditional amino acid derivatives.

Synonyms
Boc-L-His(Tos)-Merrifield resin
MDL Number
MFCD00801202
Substitution
0.25 - 1.0 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Boc-L-His(Tos)-Merrifield resin
MDL Number
MFCD00801202
Substitution
0.25 - 1.0 meq/g
Mesh Size
100 - 200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-4-toluenesulfonyl-L-histidine Merrifield is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the solid-phase synthesis of peptides, allowing researchers to create complex protein structures efficiently.
  • Drug Development: Its role in modifying amino acids enhances the design of peptide-based drugs, improving their stability and bioavailability, which is crucial in pharmaceutical research.
  • Bioconjugation: The compound is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in developing targeted therapies and diagnostics.
  • Research in Cancer Therapeutics: Its unique properties allow for the development of novel cancer treatments by enabling the design of peptides that can selectively target cancer cells.
  • Protein Engineering: This chemical aids in the modification of proteins, enhancing their functionality and stability, which is vital for applications in biotechnology and enzyme engineering.

Citations