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Catalog Number:
02721
CAS Number:
114873-13-1
Boc-3,4-dichloro-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-D-Phe(3,4-DiCl)-OH, Boc-D-Phe(3,4-Cl2)-OH
Documents
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Product Information

Boc-3,4-dichloro-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and solubility, making it an ideal candidate for various applications in pharmaceutical research and development. Its unique structure, characterized by the presence of dichlorophenyl and a chiral center, allows for the synthesis of peptides with specific biological activities, particularly in the development of novel therapeutics targeting various diseases.

Researchers and industry professionals appreciate Boc-3,4-dichloro-D-phenylalanine for its role in the synthesis of bioactive peptides, which can be used in drug discovery and development. Its ability to facilitate the introduction of chlorine substituents into peptide chains can lead to compounds with enhanced potency and selectivity. This compound is particularly relevant in the fields of oncology and neurology, where modified peptides are being explored for their therapeutic potential. With its favorable properties and applications, Boc-3,4-dichloro-D-phenylalanine stands out as a valuable tool for advancing research in peptide-based therapies.

Synonyms
Boc-D-Phe(3,4-DiCl)-OH, Boc-D-Phe(3,4-Cl2)-OH
CAS Number
114873-13-1
Purity
≥ 98% (HPLC)
Molecular Formula
C14H17Cl2NO4
Molecular Weight
334.2
MDL Number
MFCD00151887
PubChem ID
3542773
Melting Point
120 - 124 °C
Appearance
White to off-white powder
Optical Rotation
[a]22D = -28 ± 2 º (C=1.020 in EtOAc)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-D-Phe(3,4-DiCl)-OH, Boc-D-Phe(3,4-Cl2)-OH
CAS Number
114873-13-1
Purity
≥ 98% (HPLC)
Molecular Formula
C14H17Cl2NO4
Molecular Weight
334.2
MDL Number
MFCD00151887
PubChem ID
3542773
Melting Point
120 - 124 °C
Appearance
White to off-white powder
Optical Rotation
[a]22D = -28 ± 2 º (C=1.020 in EtOAc)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3,4-dichloro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of peptide-based drugs, enhancing the efficiency of drug discovery processes.
  • Pharmaceutical Development: It is used in the design of novel therapeutic agents, especially in targeting specific receptors, which can lead to more effective treatments with fewer side effects.
  • Biochemical Research: Researchers employ this compound to study protein interactions and enzyme activity, providing insights into metabolic pathways and disease mechanisms.
  • Drug Delivery Systems: Its properties make it suitable for formulating drug delivery systems that improve the bioavailability of therapeutic compounds, ensuring that medications are more effective.
  • Analytical Chemistry: This chemical is utilized in analytical methods to quantify and analyze various biological samples, aiding in the quality control of pharmaceutical products.

Citations