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Catalog Number:
02704
CAS Number:
61070-22-2
Boc-His(3-Me)-OH
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-His(π-Me)-OH, Boc-N-π-methyl-L-histidine
Documents
$55.00 /100MG
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Product Information

Boc-His(3-Me)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protected histidine residue, making it an essential building block for the development of bioactive peptides and proteins. Its unique structure, characterized by the presence of a 3-methylimidazole group, enhances its stability and solubility, which are crucial for various applications in drug formulation and biochemistry. Researchers often leverage Boc-His(3-Me)-OH in the synthesis of peptide-based therapeutics, where precise control over amino acid sequences is vital for achieving desired biological activities.

In addition to its role in peptide synthesis, Boc-His(3-Me)-OH is also employed in the study of enzyme interactions and protein folding. Its protective Boc group allows for selective deprotection during synthesis, facilitating the incorporation of histidine into complex molecular architectures. This compound stands out due to its ability to enhance the pharmacokinetic properties of peptides, making it a preferred choice for researchers focused on developing novel therapeutic agents. With its broad applicability and significant advantages in peptide chemistry, Boc-His(3-Me)-OH is an indispensable tool for professionals in the pharmaceutical and biotechnological fields.

Synonyms
Boc-L-His(π-Me)-OH, Boc-N-π-methyl-L-histidine
CAS Number
61070-22-2
Purity
≥ 99% (HPLC)
Molecular Formula
C12H19N3O4
Molecular Weight
269.3
MDL Number
MFCD00076945
PubChem ID
18510577
Appearance
White to off-white powder
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-His(π-Me)-OH, Boc-N-π-methyl-L-histidine
CAS Number
61070-22-2
Purity
≥ 99% (HPLC)
Molecular Formula
C12H19N3O4
Molecular Weight
269.3
MDL Number
MFCD00076945
PubChem ID
18510577
Appearance
White to off-white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-His(3-Me)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require protected amino acids for stability during chemical reactions.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, enhancing bioactivity and specificity in therapeutic applications.
  • Bioconjugation: Researchers use it to create bioconjugates, which are essential in targeted drug delivery systems, improving the efficacy of treatments while minimizing side effects.
  • Protein Engineering: The compound aids in modifying proteins to study their functions and interactions, which is crucial for understanding biological processes and developing new biotechnologies.
  • Diagnostics: It is also applied in the development of diagnostic tools, such as biosensors, that can detect specific biomolecules, enhancing the accuracy of medical tests.

Citations