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Catalog Number:
02700
CAS Number:
137506-13-9
Boc-L-glutamic acid α-cyclohexyl ester
Purity:
≥ 98% (Assay by Titration)
Synonym(s):
Boc-L-Glu-OcHex
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Product Information

Boc-L-glutamic acid a-cyclohexyl ester is a valuable compound widely utilized in peptide synthesis and pharmaceutical research. This derivative of glutamic acid features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and solubility, making it an ideal choice for the synthesis of complex peptides and amino acid derivatives. Its unique cyclohexyl ester functionality offers improved lipophilicity, which can facilitate better membrane permeability in drug design applications. Researchers often leverage this compound in the development of prodrugs and targeted delivery systems, where its ability to mask functional groups can enhance bioavailability and reduce toxicity.

In addition to its applications in medicinal chemistry, Boc-L-glutamic acid a-cyclohexyl ester serves as a versatile building block in the synthesis of various bioactive compounds. Its structural features allow for modifications that can lead to the creation of novel therapeutic agents. The compound's compatibility with standard coupling reactions further underscores its utility in organic synthesis, making it a preferred choice for chemists looking to streamline their workflows while achieving high yields.

Synonyms
Boc-L-Glu-OcHex
CAS Number
137506-13-9
Purity
≥ 98% (Assay by Titration)
Molecular Formula
C16H27NO6
Molecular Weight
329.4
MDL Number
MFCD00076928
PubChem ID
69913906
Melting Point
89-93 ºC
Appearance
White powder
Optical Rotation
[α]D20 = -30 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Glu-OcHex
CAS Number
137506-13-9
Purity
≥ 98% (Assay by Titration)
Molecular Formula
C16H27NO6
Molecular Weight
329.4
MDL Number
MFCD00076928
PubChem ID
69913906
Melting Point
89-93 ºC
Appearance
White powder
Optical Rotation
[α]D20 = -30 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamic acid a-cyclohexyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups. This is crucial for creating complex peptides in pharmaceuticals.
  • Drug Development: Its application in drug formulation helps in enhancing the solubility and stability of active pharmaceutical ingredients, leading to more effective medications with improved bioavailability.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Research in Neuroscience: It plays a role in studying neurotransmitter pathways, particularly in the synthesis of glutamate derivatives, which are vital for understanding neurological functions and disorders.
  • Analytical Chemistry: This compound is employed in analytical techniques to detect and quantify amino acids in various samples, aiding researchers in food science and quality control.

Citations